biostudies-literatureUnknown24(2)Kim DHKorean Liver Cancer Association<h4>Backgrounds/aims</h4>To systematically evaluate inter-reader agreement in the assessment of individual liver imaging reporting and data system (LI-RADS) category M (LR-M) imaging features in computed tomography/magnetic resonance imaging (CT/MRI) LIRADS v2018, and to explore the causes of poor agreement in LR-M assignment.<h4>Methods</h4>Original studies reporting inter-reader agreement for LR-M features on multiphasic CT or MRI were identified using the MEDLINE, EMBASE, and Cochrane databases. The pooled kappa coefficient (κ) was calculated using the DerSimonian-Laird random-effects model. Heterogeneity was assessed using Cochran's Q test and I2 statistics. Subgroup meta-regression analyses were conducted to explore the study heterogeneity.<h4>Results</h4>In total, 24 eligible studiesJournal of liver cancer192-205https://www.ebi.ac.uk/biostudies/studies/S-EPMC11449575biostudies-literatureInter-reader agreement for CT/MRI LI-RADS category M imaging features: a systematic review and meta-analysis.PMC11449575Kim DHChoi SHfalseInter-reader agreement for CT/MRI LI-RADS category M imaging features: a systematic review and meta-analysis.<h4>Backgrounds/aims</h4>To systematically evaluate inter-reader agreement in the assessment of individual liver imaging reporting and data system (LI-RADS) category M (LR-M) imaging features in computed tomography/magnetic resonance imaging (CT/MRI) LIRADS v2018, and to explore the causes of poor agreement in LR-M assignment.<h4>Methods</h4>Original studies reporting inter-reader agreement for LR-M features on multiphasic CT or MRI were identified using the MEDLINE, EMBASE, and Cochrane databases. The pooled kappa coefficient (κ) was calculated using the DerSimonian-Laird random-effects model. Heterogeneity was assessed using Cochran's Q test and I2 statistics. Subgroup meta-regression analyses were conducted to explore the study heterogeneity.<h4>Results</h4>In total, 24 eligible studies2024-01-01T00:00:00Z2024 Sep2025-04-18T13:05:29.844Z2025-04-06T22:36:39.922ZS-EPMC114495753861654310.17998/jlc.2024.04.05