{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Melgarejo JD"],"funding":["NIA NIH HHS"],"pagination":["1985-1993"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11449671"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["42(11)"],"pubmed_abstract":["<h4>Objective</h4>A high office blood pressure (BP) is associated with cognitive decline. However, evidence of 24-h ambulatory BP monitoring is limited, and no studies have investigated whether longitudinal changes in 24-h BP are associated with cognitive decline. We aimed to test whether higher longitudinal changes in 24-h ambulatory BP measurements are associated with cognitive decline.<h4>Methods</h4>We included 437 dementia-free participants from the Maracaibo Aging Study with prospective data on 24-h ambulatory BP monitoring and cognitive function, which was assessed using the selective reminding test (SRT) and the Mini-Mental State Examination (MMSE). Using multivariate linear mixed regression models, we analyzed the association between longitudinal changes in measures of 24-h ambula"],"journal":["Journal of hypertension"],"pubmed_title":["Association of longitudinal changes in 24-h blood pressure level and variability with cognitive decline."],"pmcid":["PMC11449671"],"funding_grant_id":["P30 AG059305","DP1 AG069870","P30 AG066546","R01 AG036469","R03 AG054186"],"pubmed_authors":["Mena LJ","Patil D","Vatcheva KP","Terwilliger JD","Mejia-Arango S","Blangero J","Charisis S","Chavez CA","Mavarez RP","Satizabal CL","Alliey-Rodriguez N","Seshadri S","Maestre GE","Garcia A","Gaona C","Melgarejo JD","Silva E","Lee JH"],"additional_accession":[]},"is_claimable":false,"name":"Association of longitudinal changes in 24-h blood pressure level and variability with cognitive decline.","description":"<h4>Objective</h4>A high office blood pressure (BP) is associated with cognitive decline. However, evidence of 24-h ambulatory BP monitoring is limited, and no studies have investigated whether longitudinal changes in 24-h BP are associated with cognitive decline. We aimed to test whether higher longitudinal changes in 24-h ambulatory BP measurements are associated with cognitive decline.<h4>Methods</h4>We included 437 dementia-free participants from the Maracaibo Aging Study with prospective data on 24-h ambulatory BP monitoring and cognitive function, which was assessed using the selective reminding test (SRT) and the Mini-Mental State Examination (MMSE). Using multivariate linear mixed regression models, we analyzed the association between longitudinal changes in measures of 24-h ambula","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-05T08:38:43.94Z","creation":"2025-04-06T16:26:20.798Z"},"accession":"S-EPMC11449671","cross_references":{"pubmed":["39146553"],"doi":["10.1097/HJH.0000000000003824"]}}