{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Luo C"],"pubmed_abstract":["<h4>Background</h4>CMRtools is a software package that can be used to measure T2* values to diagnose liver iron overload, however, its accuracy in terms is affected by multiple factors, including goodness-of-fit (R<sup>2</sup> value), the number of echo time (TE) images, and the liver iron concentration (LIC). To investigate the effects of the R<sup>2</sup> value, the number of TE images, and the LIC on the accuracy of CMRtools software for measuring T2* values to diagnose liver iron overload (LIO).<h4>Materials and methods</h4>CMRtools software was used to measure liver T2* values among 108 thalassemia patients via the truncation method, and the R<sup>2</sup> values, the number of TE images, and T2* values were recorded. These values were subsequently converted into liver iron concentrati"],"journal":["Frontiers in medicine"],"pagination":["1424294"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11449772"],"repository":["biostudies-literature"],"pubmed_title":["Assessing the accuracy of CMRtools software for diagnosing liver iron overload in thalassemia patients: influencing factors and optimisation strategies."],"pmcid":["PMC11449772"],"pubmed_authors":["Peng F","Huang C","Zhang Y","Tang C","Peng P","Liang L","Ning X","Xu F","Luo C"],"additional_accession":[]},"is_claimable":false,"name":"Assessing the accuracy of CMRtools software for diagnosing liver iron overload in thalassemia patients: influencing factors and optimisation strategies.","description":"<h4>Background</h4>CMRtools is a software package that can be used to measure T2* values to diagnose liver iron overload, however, its accuracy in terms is affected by multiple factors, including goodness-of-fit (R<sup>2</sup> value), the number of echo time (TE) images, and the liver iron concentration (LIC). To investigate the effects of the R<sup>2</sup> value, the number of TE images, and the LIC on the accuracy of CMRtools software for measuring T2* values to diagnose liver iron overload (LIO).<h4>Materials and methods</h4>CMRtools software was used to measure liver T2* values among 108 thalassemia patients via the truncation method, and the R<sup>2</sup> values, the number of TE images, and T2* values were recorded. These values were subsequently converted into liver iron concentrati","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2025-04-26T08:45:06.792Z","creation":"2025-04-06T12:52:29.42Z"},"accession":"S-EPMC11449772","cross_references":{"pubmed":["39371340"],"doi":["10.3389/fmed.2024.1424294"]}}