{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Ambrosch P"],"pubmed_abstract":["<h4>Background</h4>A limited number of single institutions have published retrospective cohort studies on transoral laser microsurgery for supraglottic laryngectomy (TLM-SGL). These studies have shown that the oncologic outcomes of TLM-SGL are comparable to those of open SGL. However, there is limited information available regarding swallowing rehabilitation and quality of life (QoL).<h4>Patients and methods</h4>SUPRATOL is a prospective, multicenter trial assessing the functional outcomes of TLM-SGL +/- adjuvant radio-(chemo)-therapy. The primary endpoint was aspiration-free swallowing at 12 months, as established using fibreoptic endoscopic evaluation of swallowing (FEES) and defined as a grade < 6 on the penetration-aspiration scale. Secondary endpoints were swallowing- and voice-relate"],"journal":["Frontiers in oncology"],"pagination":["1440024"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11449847"],"repository":["biostudies-literature"],"pubmed_title":["Transoral laser microsurgery for supraglottic carcinomas: results of a prospective multicenter trial (SUPRATOL)."],"pmcid":["PMC11449847"],"pubmed_authors":["Weiß S","Wittekindt C","Plontke SK","Tostmann R","Schroeder U","Scherl C","Hilber H","Linxweiler M","Knipping S","Fietkau R","Deitmer T","Breitenstein K","Harreus U","Vester S","Meuret S","Schilling V","Psychogios G","Lammert A","Arens C","Dietz A","Bartel S","Grosheva M","Koscielny S","Borzikowsky C","Fazel A","Kunzel J","Jackel MC","Oeken J","Scheich M","Delank KW","Veit JA","Boeger D","Ambrosch P","Greve J"],"additional_accession":[]},"is_claimable":false,"name":"Transoral laser microsurgery for supraglottic carcinomas: results of a prospective multicenter trial (SUPRATOL).","description":"<h4>Background</h4>A limited number of single institutions have published retrospective cohort studies on transoral laser microsurgery for supraglottic laryngectomy (TLM-SGL). These studies have shown that the oncologic outcomes of TLM-SGL are comparable to those of open SGL. However, there is limited information available regarding swallowing rehabilitation and quality of life (QoL).<h4>Patients and methods</h4>SUPRATOL is a prospective, multicenter trial assessing the functional outcomes of TLM-SGL +/- adjuvant radio-(chemo)-therapy. The primary endpoint was aspiration-free swallowing at 12 months, as established using fibreoptic endoscopic evaluation of swallowing (FEES) and defined as a grade < 6 on the penetration-aspiration scale. Secondary endpoints were swallowing- and voice-relate","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2025-04-22T21:47:05.491Z","creation":"2025-04-22T21:47:05.491Z"},"accession":"S-EPMC11449847","cross_references":{"pubmed":["39372873"],"doi":["10.3389/fonc.2024.1440024"]}}