biostudies-literatureUnknown14Ambrosch P<h4>Background</h4>A limited number of single institutions have published retrospective cohort studies on transoral laser microsurgery for supraglottic laryngectomy (TLM-SGL). These studies have shown that the oncologic outcomes of TLM-SGL are comparable to those of open SGL. However, there is limited information available regarding swallowing rehabilitation and quality of life (QoL).<h4>Patients and methods</h4>SUPRATOL is a prospective, multicenter trial assessing the functional outcomes of TLM-SGL +/- adjuvant radio-(chemo)-therapy. The primary endpoint was aspiration-free swallowing at 12 months, as established using fibreoptic endoscopic evaluation of swallowing (FEES) and defined as a grade < 6 on the penetration-aspiration scale. Secondary endpoints were swallowing- and voice-relateFrontiers in oncology1440024https://www.ebi.ac.uk/biostudies/studies/S-EPMC11449847biostudies-literatureTransoral laser microsurgery for supraglottic carcinomas: results of a prospective multicenter trial (SUPRATOL).PMC11449847Weiß SWittekindt CPlontke SKTostmann RSchroeder UScherl CHilber HLinxweiler MKnipping SFietkau RDeitmer TBreitenstein KHarreus UVester SMeuret SSchilling VPsychogios GLammert AArens CDietz ABartel SGrosheva MKoscielny SBorzikowsky CFazel AKunzel JJackel MCOeken JScheich MDelank KWVeit JABoeger DAmbrosch PGreve JfalseTransoral laser microsurgery for supraglottic carcinomas: results of a prospective multicenter trial (SUPRATOL).<h4>Background</h4>A limited number of single institutions have published retrospective cohort studies on transoral laser microsurgery for supraglottic laryngectomy (TLM-SGL). These studies have shown that the oncologic outcomes of TLM-SGL are comparable to those of open SGL. However, there is limited information available regarding swallowing rehabilitation and quality of life (QoL).<h4>Patients and methods</h4>SUPRATOL is a prospective, multicenter trial assessing the functional outcomes of TLM-SGL +/- adjuvant radio-(chemo)-therapy. The primary endpoint was aspiration-free swallowing at 12 months, as established using fibreoptic endoscopic evaluation of swallowing (FEES) and defined as a grade < 6 on the penetration-aspiration scale. Secondary endpoints were swallowing- and voice-relate2024-01-01T00:00:00Z20242025-04-22T21:47:05.491Z2025-04-22T21:47:05.491ZS-EPMC114498473937287310.3389/fonc.2024.1440024