{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lin Z"],"funding":["Medical Research Council Centre for Medical Mycology","Engineering and Physical Sciences Research Council"],"pagination":["e0308664"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11452003"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(10)"],"pubmed_abstract":["This study aims at improving the lower-limb muscle segmentation accuracy of deep learning approaches based on Magnetic Resonance Imaging (MRI) scans, crucial for the diagnostic and therapeutic processes in musculoskeletal diseases. In general, segmentation methods such as U-Net deep learning neural networks can achieve good Dice Similarity Coefficient (DSC) values, e.g. around 0.83 to 0.91 on various cohorts. Some generic post-processing strategies have been studied to incorporate connectivity constraints into the resulting masks for the purpose of further improving the segmentation accuracy. In this paper, a novel mean shape (MS) based post-processing method is proposed, utilizing Statistical Shape Modelling (SSM) to fine-tune the segmentation output, taking into consideration the muscle "],"journal":["PloS one"],"pubmed_title":["A novel mean shape based post-processing method for enhancing deep learning lower-limb muscle segmentation accuracy."],"pmcid":["PMC11452003"],"funding_grant_id":["MR/R502182/1","EP/K03877X/1","EP/S032940/1"],"pubmed_authors":["Guo L","Lin Z","Dall'Ara E"],"additional_accession":[]},"is_claimable":false,"name":"A novel mean shape based post-processing method for enhancing deep learning lower-limb muscle segmentation accuracy.","description":"This study aims at improving the lower-limb muscle segmentation accuracy of deep learning approaches based on Magnetic Resonance Imaging (MRI) scans, crucial for the diagnostic and therapeutic processes in musculoskeletal diseases. In general, segmentation methods such as U-Net deep learning neural networks can achieve good Dice Similarity Coefficient (DSC) values, e.g. around 0.83 to 0.91 on various cohorts. Some generic post-processing strategies have been studied to incorporate connectivity constraints into the resulting masks for the purpose of further improving the segmentation accuracy. In this paper, a novel mean shape (MS) based post-processing method is proposed, utilizing Statistical Shape Modelling (SSM) to fine-tune the segmentation output, taking into consideration the muscle ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-06-13T05:41:03.434Z","creation":"2025-04-06T12:32:33.849Z"},"accession":"S-EPMC11452003","cross_references":{"pubmed":["39365764"],"doi":["10.1371/journal.pone.0308664"]}}