{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhou XD"],"funding":["National Natural Science Foundation of China","National Key Research and Development Program of China"],"pagination":["102848"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11462227"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["76"],"pubmed_abstract":["<h4>Background</h4>Obesity represents a major global health challenge with important clinical implications. Despite its recognized importance, the global disease burden attributable to high body mass index (BMI) remains less well understood.<h4>Methods</h4>We systematically analyzed global deaths and disability-adjusted life years (DALYs) attributable to high BMI using the methodology and analytical approaches of the Global Burden of Disease Study (GBD) 2021. High BMI was defined as a BMI over 25 kg/m<sup>2</sup> for individuals aged ≥20 years. The Socio-Demographic Index (SDI) was used as a composite measure to assess the level of socio-economic development across different regions. Subgroup analyses considered age, sex, year, geographical location, and SDI.<h4>Findings</h4>From 1990 to 2"],"journal":["EClinicalMedicine"],"pubmed_title":["Burden of disease attributable to high body mass index: an analysis of data from the Global Burden of Disease Study 2021."],"pmcid":["PMC11462227"],"funding_grant_id":["2023YFA1800801","82070588","82370577"],"pubmed_authors":["Chan WK","Zuluaga M","Casajoana A","Pik-Shan Kong A","Wong YJ","Ruiz-Ucar E","Zhang H","Thaher O","Oviedo RJ","Toro-Huamanchumo CJ","Al Momani H","Abdelbaki TN","Szepietowski O","Zheng MH","Perera N","Al-Busafi SA","Jumaev NA","Ospanov O","Garcia M","Mendez-Sanchez N","Sharara AI","Lim-Loo MC","Yang W","Misra A","Fouad Y","Ocama P","Prasad A","Yen Kok KY","Abu-Abeid A","Targher G","Robertson AG","Ryan JD","Valenti L","Alswat K","Molina GA","Mantzoros CS","Byrne CD","Kızılkaya MC","Lonardo A","Ataya K","Ali A","Katsouras CS","Zhou XD","Opio CK","Treeprasertsuk S","Luo F","Sookoian S","Adams L","Abbas SI","Viveiros O","Chen QF"],"additional_accession":[]},"is_claimable":false,"name":"Burden of disease attributable to high body mass index: an analysis of data from the Global Burden of Disease Study 2021.","description":"<h4>Background</h4>Obesity represents a major global health challenge with important clinical implications. Despite its recognized importance, the global disease burden attributable to high body mass index (BMI) remains less well understood.<h4>Methods</h4>We systematically analyzed global deaths and disability-adjusted life years (DALYs) attributable to high BMI using the methodology and analytical approaches of the Global Burden of Disease Study (GBD) 2021. High BMI was defined as a BMI over 25 kg/m<sup>2</sup> for individuals aged ≥20 years. The Socio-Demographic Index (SDI) was used as a composite measure to assess the level of socio-economic development across different regions. Subgroup analyses considered age, sex, year, geographical location, and SDI.<h4>Findings</h4>From 1990 to 2","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-26T10:26:26.693Z","creation":"2025-04-06T13:21:30.893Z"},"accession":"S-EPMC11462227","cross_references":{"pubmed":["39386160"],"doi":["10.1016/j.eclinm.2024.102848"]}}