biostudies-literatureHoosen FSteno Diabetes Center Copenhagen (SDCC)2768https://www.ebi.ac.uk/biostudies/studies/S-EPMC11465697biostudies-literatureUnknown24(1)<h4>Background</h4>Human Immunodeficiency Virus (HIV) and type 2 diabetes (T2D) are amongst the leading causes of death in South Africa. The preferred first-line anti-retroviral treatment contains dolutegravir (DTG), shown to increase body weight, may compound the already high rates of obesity and associated risk for T2D. South Africa has widespread food insecurity, making traditional dietary strategies difficult to implement. Time-restricted eating (TRE) may be an appropriate intervention in resource-limited communities.<h4>Methods</h4>This article outlines the development and feasibility testing of a TRE intervention to inform the design of a TRE randomised controlled trial in women (20-45 years old) living with overweight/obesity and HIV, receiving DTG-based treatment from a resource-liBMC public healthDevelopment and feasibility testing of a time-restricted eating intervention for women living with overweight/obesity and HIV in a resource-limited setting of South Africa.PMC11465697SDCC 2.G Reproduktiv sundhed og familierDave JAFærch KAagaard-Hansen JMendham AEGrunnet LGde Villiers AHoosen FGoedecke JHQuist JSPico MLfalseDevelopment and feasibility testing of a time-restricted eating intervention for women living with overweight/obesity and HIV in a resource-limited setting of South Africa.<h4>Background</h4>Human Immunodeficiency Virus (HIV) and type 2 diabetes (T2D) are amongst the leading causes of death in South Africa. The preferred first-line anti-retroviral treatment contains dolutegravir (DTG), shown to increase body weight, may compound the already high rates of obesity and associated risk for T2D. South Africa has widespread food insecurity, making traditional dietary strategies difficult to implement. Time-restricted eating (TRE) may be an appropriate intervention in resource-limited communities.<h4>Methods</h4>This article outlines the development and feasibility testing of a TRE intervention to inform the design of a TRE randomised controlled trial in women (20-45 years old) living with overweight/obesity and HIV, receiving DTG-based treatment from a resource-li2024-01-01T00:00:00Z2024 Oct2026-06-15T06:22:54.475Z2025-04-04T19:38:20.617ZS-EPMC114656973939049810.1186/s12889-024-20228-y