{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["33(42)"],"submitter":["Ruland A"],"pubmed_abstract":["Precision surface engineering is key to advanced biomaterials. A new platform of PEGylated styrene-maleic acid copolymers for adsorptive surface biofunctionalization is reported. Balanced amphiphilicity renders the copolymers water-soluble but strongly affine for surfaces. Fine-tuning of their molecular architecture provides control over adsorptive anchorage onto specific materials-which is why they are referred to as \"anchor polymers\" (APs)-and over structural characteristics of the adsorbed layers. Conjugatable with an array of bioactives-including cytokine-complexing glycosaminoglycans, cell-adhesion-mediating peptides and antimicrobials-APs can be applied to customize materials for demanding biotechnologies in uniquely versatile, simple, and robust ways. Moreover, homo- and heterodispl"],"journal":["Advanced materials (Deerfield Beach, Fla.)"],"pagination":["e2102489"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11468472"],"repository":["biostudies-literature"],"pubmed_title":["Amphiphilic Copolymers for Versatile, Facile, and In Situ Tunable Surface Biofunctionalization."],"pmcid":["PMC11468472"],"pubmed_authors":["Ruland A","Schirmer L","Valtin J","Helmecke T","Hahn D","Freudenberg U","MacDonald W","Renner LD","Friedrichs J","Schwartz VB","Schenker S","Meinhardt A","Sikosana MKLN","Konradi R","Werner C","Kaiser N"],"additional_accession":[]},"is_claimable":false,"name":"Amphiphilic Copolymers for Versatile, Facile, and In Situ Tunable Surface Biofunctionalization.","description":"Precision surface engineering is key to advanced biomaterials. A new platform of PEGylated styrene-maleic acid copolymers for adsorptive surface biofunctionalization is reported. Balanced amphiphilicity renders the copolymers water-soluble but strongly affine for surfaces. Fine-tuning of their molecular architecture provides control over adsorptive anchorage onto specific materials-which is why they are referred to as \"anchor polymers\" (APs)-and over structural characteristics of the adsorbed layers. Conjugatable with an array of bioactives-including cytokine-complexing glycosaminoglycans, cell-adhesion-mediating peptides and antimicrobials-APs can be applied to customize materials for demanding biotechnologies in uniquely versatile, simple, and robust ways. Moreover, homo- and heterodispl","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-05T23:44:43.693Z","creation":"2025-04-05T23:44:43.693Z"},"accession":"S-EPMC11468472","cross_references":{"pubmed":["34431569"],"doi":["10.1002/adma.202102489"]}}