{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Geng H"],"funding":["Rosetrees Trust","British Heart Foundation","Medical Research Council","Karolinska Institutet","European Commission","Wellcome Trust","Biotechnology and Biological Sciences Research Council"],"pagination":["e2301148"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11468501"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(27)"],"pubmed_abstract":["The development of near-infrared light responsive conductive polymers provides a useful theranostic platform for malignant tumors by maximizing spatial resolution with deep tissue penetration for diagnosis and photothermal therapy. Herein, the self-assembly of ultrathin 2D polypyrrole nanosheets utilizing dopamine as a capping agent and a monolayer of octadecylamine as a template is demonstrated. The 2D polypyrrole-polydopamine nanostructure has tunable size distribution which shows strong absorption in the first and second near-infrared windows, enabling photoacoustic imaging and photothermal therapy. The hybrid double-layer is demonstrated to increase Raman intensity for 3D Raman imaging (up to two orders of magnitude enhancement and spatial resolution up to 1 µm). The acidic environment"],"journal":["Advanced healthcare materials"],"pubmed_title":["Hybrid Polypyrrole and Polydopamine Nanosheets for Precise Raman/Photoacoustic Imaging and Photothermal Therapy."],"pmcid":["PMC11468501"],"funding_grant_id":["FS/15/33/31608","BB/M009513/1","FS/SBSRF/21/31020","RM/17/1/33377","212937/Z/18/Z","101028152","MR/R026416/1"],"pubmed_authors":["Li X","Geng H","Sun R","Grigsby CL","Brachi G","Stuckey DJ","Ma Y","Lupton EJ","Stevens MM","Zhou K"],"additional_accession":[]},"is_claimable":false,"name":"Hybrid Polypyrrole and Polydopamine Nanosheets for Precise Raman/Photoacoustic Imaging and Photothermal Therapy.","description":"The development of near-infrared light responsive conductive polymers provides a useful theranostic platform for malignant tumors by maximizing spatial resolution with deep tissue penetration for diagnosis and photothermal therapy. Herein, the self-assembly of ultrathin 2D polypyrrole nanosheets utilizing dopamine as a capping agent and a monolayer of octadecylamine as a template is demonstrated. The 2D polypyrrole-polydopamine nanostructure has tunable size distribution which shows strong absorption in the first and second near-infrared windows, enabling photoacoustic imaging and photothermal therapy. The hybrid double-layer is demonstrated to increase Raman intensity for 3D Raman imaging (up to two orders of magnitude enhancement and spatial resolution up to 1 µm). The acidic environment","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Oct","modification":"2026-07-15T13:12:28.882Z","creation":"2025-04-06T12:29:51.065Z"},"accession":"S-EPMC11468501","cross_references":{"pubmed":["37169351"],"doi":["10.1002/adhm.202301148"]}}