biostudies-literatureUnknown39(1)Ota E<h4>Purpose</h4>Diverting ileostomy is related to postoperative high-output stoma (HOS) leading to kidney injury. The purpose of our study was to clarify the risk factors for ileostomy-associated kidney injury, which is kidney injury starting after the first operation to ileostomy closure after colorectal tumor surgery with diverting ileostomy.<h4>Methods</h4>Between January 2013 and December 2020, 442 patients who underwent colorectal tumor surgery (cancer, neuroendocrine tumor, and leiomyosarcoma) following diverting ileostomy formation were included. We used the KDIGO (Kidney Disease Improving Global Outcomes) guidelines, which defines the acute kidney injury (AKI) to classify patients with ileostomy-associated kidney injury. The definition of AKI was (i) serum creatinine (sCr) ≥ 0.3 mgInternational journal of colorectal disease160https://www.ebi.ac.uk/biostudies/studies/S-EPMC11471691biostudies-literaturePreoperative risk factors for ileostomy-associated kidney injury in colorectal tumor surgery following ileostomy formation.PMC11471691Nakagawa KOzawa MWatanabe JEndo IHirai TOta ESuwa HSuwa YIshibe AfalsePreoperative risk factors for ileostomy-associated kidney injury in colorectal tumor surgery following ileostomy formation.<h4>Purpose</h4>Diverting ileostomy is related to postoperative high-output stoma (HOS) leading to kidney injury. The purpose of our study was to clarify the risk factors for ileostomy-associated kidney injury, which is kidney injury starting after the first operation to ileostomy closure after colorectal tumor surgery with diverting ileostomy.<h4>Methods</h4>Between January 2013 and December 2020, 442 patients who underwent colorectal tumor surgery (cancer, neuroendocrine tumor, and leiomyosarcoma) following diverting ileostomy formation were included. We used the KDIGO (Kidney Disease Improving Global Outcomes) guidelines, which defines the acute kidney injury (AKI) to classify patients with ileostomy-associated kidney injury. The definition of AKI was (i) serum creatinine (sCr) ≥ 0.3 mg2024-01-01T00:00:00Z2024 Oct2025-04-04T07:40:41.125Z2025-04-04T07:40:41.125ZS-EPMC114716913939717710.1007/s00384-024-04732-6