{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tabarak S"],"funding":["National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["434"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11471876"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["Memory reprocessing during sleep is a well-established phenomenon in numerous studies. However, it is unclear whether the intensity of memory reprocessing is consistently maintained throughout the night or exhibits dynamic changes. This study investigates the temporal dynamics of negative emotional memory reprocessing during sleep, with a specific focus on slow oscillation (SO)-spindle coupling and its role in memory reprocessing. In the first experiment (N = 40, mean age = 22.5 years), we detected the negative emotional memory reprocessing strength in each sleep cycle, we found that the 2nd sleep cycle after negative emotional memory learning constitute the most sensitive window for memory reprocessing, furthermore, SO-spindle coupling signals in this window plays a role in stabilizing ne"],"journal":["Translational psychiatry"],"pubmed_title":["Temporal dynamics of negative emotional memory reprocessing during sleep."],"pmcid":["PMC11471876"],"funding_grant_id":["82288101","82071490"],"pubmed_authors":["Tabarak S","Shi L","Bao Y","Weber FD","Deng J","Li P","Yuan K","Gong Y","Fan T","Lu L","Li S","Zhu X","Shi J"],"additional_accession":[]},"is_claimable":false,"name":"Temporal dynamics of negative emotional memory reprocessing during sleep.","description":"Memory reprocessing during sleep is a well-established phenomenon in numerous studies. However, it is unclear whether the intensity of memory reprocessing is consistently maintained throughout the night or exhibits dynamic changes. This study investigates the temporal dynamics of negative emotional memory reprocessing during sleep, with a specific focus on slow oscillation (SO)-spindle coupling and its role in memory reprocessing. In the first experiment (N = 40, mean age = 22.5 years), we detected the negative emotional memory reprocessing strength in each sleep cycle, we found that the 2nd sleep cycle after negative emotional memory learning constitute the most sensitive window for memory reprocessing, furthermore, SO-spindle coupling signals in this window plays a role in stabilizing ne","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-04T11:04:12.531Z","creation":"2025-04-04T11:04:12.531Z"},"accession":"S-EPMC11471876","cross_references":{"pubmed":["39397004"],"doi":["10.1038/s41398-024-03146-w"]}}