{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bounds AD"],"funding":["Medical Research Council Canada","Medical Research Council","European Regional Development Fund"],"pagination":["e202000481"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11475348"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(5)"],"pubmed_abstract":["Multiwell plates (MWPs) are the workhorses of the life sciences. However, biophotonics research with MWPs is limited, in part due to the lack of equipment suitable for photo-irradiation of photoactive molecules in a MWP-suitable, high-throughput manner, either commercially or through open-source MWP systems. Here we present \"LightBox\", a calibrated controllable MWP illumination system with broad applications including screening of photoactive molecules and characterization of photocatalytic chemicals. LightBox is a high intensity, accurately controllable, uniform illumination system designed for MWPs with electronics and a control unit that provides a simple and intuitive interface. LightBox can reach intensities of 0.23 mW/mm<sup>2</sup> at wavelengths of 405 nm with variance between well"],"journal":["Journal of biophotonics"],"pubmed_title":["LightBox: A multiwell plate illumination system for photoactive molecule characterization."],"pmcid":["PMC11475348"],"funding_grant_id":["25R16P01361","Confidence in Concept award"],"pubmed_authors":["Bounds AD","Bailey RD","Adams CT","Callaghan DC","Girkin JM"],"additional_accession":[]},"is_claimable":false,"name":"LightBox: A multiwell plate illumination system for photoactive molecule characterization.","description":"Multiwell plates (MWPs) are the workhorses of the life sciences. However, biophotonics research with MWPs is limited, in part due to the lack of equipment suitable for photo-irradiation of photoactive molecules in a MWP-suitable, high-throughput manner, either commercially or through open-source MWP systems. Here we present \"LightBox\", a calibrated controllable MWP illumination system with broad applications including screening of photoactive molecules and characterization of photocatalytic chemicals. LightBox is a high intensity, accurately controllable, uniform illumination system designed for MWPs with electronics and a control unit that provides a simple and intuitive interface. LightBox can reach intensities of 0.23 mW/mm<sup>2</sup> at wavelengths of 405 nm with variance between well","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-26T07:57:14.495Z","creation":"2025-04-06T12:31:46.891Z"},"accession":"S-EPMC11475348","cross_references":{"pubmed":["33576569"],"doi":["10.1002/jbio.202000481"]}}