biostudies-literatureUnknown13(9)Ji Y<h4>Background</h4>The prognostic predictors of the synchronous multiple primary lung cancer (SMPLC) still remain unclear, and there is a lack of studies on the prognosis of SMPLC patients excluding those with multifocal ground-glass/lepidic (GG/L) nodules. The aim of this study is to develop an effective model for predicting survival of SMPLC patients.<h4>Methods</h4>In this multicenter cohort study, a total of 831 SMPLC patients presenting for lung cancer resection from January 2004 to January 2018 at five institutions were included for developing and validating a nomogram model. Specifically, 499 patients from the Cancer Hospital, Chinese Academy of Medical Sciences, and Beijing Chao-Yang Hospital, Capital Medical University were served as the training cohort. A total of 332 patients frTranslational lung cancer research2254-2268https://www.ebi.ac.uk/biostudies/studies/S-EPMC11484729biostudies-literatureEstablishment of a survival predictive model for patients with two synchronous multiple primary lung cancers: a multicenter cohort analysis.PMC11484729Qi LAi SYuan LHu BLiu YXie HZhao QFu HTao YQiu BFeng WJi YWang XBai GGao SRong LJin LZhou JfalseEstablishment of a survival predictive model for patients with two synchronous multiple primary lung cancers: a multicenter cohort analysis.<h4>Background</h4>The prognostic predictors of the synchronous multiple primary lung cancer (SMPLC) still remain unclear, and there is a lack of studies on the prognosis of SMPLC patients excluding those with multifocal ground-glass/lepidic (GG/L) nodules. The aim of this study is to develop an effective model for predicting survival of SMPLC patients.<h4>Methods</h4>In this multicenter cohort study, a total of 831 SMPLC patients presenting for lung cancer resection from January 2004 to January 2018 at five institutions were included for developing and validating a nomogram model. Specifically, 499 patients from the Cancer Hospital, Chinese Academy of Medical Sciences, and Beijing Chao-Yang Hospital, Capital Medical University were served as the training cohort. A total of 332 patients fr2024-01-01T00:00:00Z2024 Sep2025-04-18T14:10:51.194Z2025-04-07T00:14:36.119ZS-EPMC114847293943031610.21037/tlcr-24-252