{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["65(11)"],"submitter":["St-Jean G"],"pubmed_abstract":["Development of gonadal tumors within an ovotestis is rare in mammals and this disturbance was not reported in cows. We report herein a gonadal stromal (granulosa cell) tumor in an ovotestis of a 15-month-old heifer from which the reproductive tract was obtained from a local slaughterhouse. Histopathological evaluation revealed that the gonads were ovotestis, but also a coincidental sex cordstromal (granulosa cell) tumor. The sex chromosome type was determined to be XX, suggesting an XX ovotesticular disorder of sexual development with uterus and a female phenotype. Key clinical message: Disorders of sexual development are common in mammals. Gonadal tumors in disorders of sexual development are rarely reported and have not been reported in cows."],"journal":["The Canadian veterinary journal = La revue veterinaire canadienne"],"pagination":["1141-1148"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11486109"],"repository":["biostudies-literature"],"pubmed_title":["Sex cord-stromal (granulosa cell) tumor in an ovotestis from a cow."],"pmcid":["PMC11486109"],"pubmed_authors":["Beaudoin G","Boyer A","Zamberlam G","Charreton-Sanford V","Pesant MJ","Gagnon CA","St-Jean G"],"additional_accession":[]},"is_claimable":false,"name":"Sex cord-stromal (granulosa cell) tumor in an ovotestis from a cow.","description":"Development of gonadal tumors within an ovotestis is rare in mammals and this disturbance was not reported in cows. We report herein a gonadal stromal (granulosa cell) tumor in an ovotestis of a 15-month-old heifer from which the reproductive tract was obtained from a local slaughterhouse. Histopathological evaluation revealed that the gonads were ovotestis, but also a coincidental sex cordstromal (granulosa cell) tumor. The sex chromosome type was determined to be XX, suggesting an XX ovotesticular disorder of sexual development with uterus and a female phenotype. Key clinical message: Disorders of sexual development are common in mammals. Gonadal tumors in disorders of sexual development are rarely reported and have not been reported in cows.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2025-04-05T10:19:01.962Z","creation":"2025-04-05T10:19:01.962Z"},"accession":"S-EPMC11486109","cross_references":{"pubmed":["39494182"]}}