biostudies-literatureUnknown15Morales LFusarium head blight (FHB) is a devastating disease of wheat, causing yield losses, reduced grain quality, and mycotoxin contamination. Breeding can mitigate the severity of FHB epidemics, especially with genomics-assisted methods. The mechanisms underlying resistance to FHB in wheat have been extensively studied, including phenological traits and genome-wide markers associated with FHB severity. Here, we aimed to improve genomic prediction for FHB resistance across breeding programs by incorporating FHB-correlated traits and FHB-associated loci as model covariates. We combined phenotypic data on FHB severity, anthesis date, and plant height with genome-wide marker data from five Central European winter wheat breeding programs for genome-wide association studies (GWAS) and genomic predictiFrontiers in plant science1454473https://www.ebi.ac.uk/biostudies/studies/S-EPMC11486744biostudies-literatureLeveraging trait and QTL covariates to improve genomic prediction of resistance to Fusarium head blight in Central European winter wheat.PMC11486744Reddy Nannuru VKLillemo MShahinnia FMorales LKempf HHolzapfel JAkdemir DBuerstmayr HNeumayer AMichel SLoschenberger FStadlmeier MIsidro-Sanchez JHartl LGirard ALfalseLeveraging trait and QTL covariates to improve genomic prediction of resistance to Fusarium head blight in Central European winter wheat.Fusarium head blight (FHB) is a devastating disease of wheat, causing yield losses, reduced grain quality, and mycotoxin contamination. Breeding can mitigate the severity of FHB epidemics, especially with genomics-assisted methods. The mechanisms underlying resistance to FHB in wheat have been extensively studied, including phenological traits and genome-wide markers associated with FHB severity. Here, we aimed to improve genomic prediction for FHB resistance across breeding programs by incorporating FHB-correlated traits and FHB-associated loci as model covariates. We combined phenotypic data on FHB severity, anthesis date, and plant height with genome-wide marker data from five Central European winter wheat breeding programs for genome-wide association studies (GWAS) and genomic predicti2024-01-01T00:00:00Z20242025-04-04T01:11:36.101Z2025-04-04T01:11:36.101ZS-EPMC114867443943089110.3389/fpls.2024.1454473