{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Grzesinski L"],"funding":["Narodowe Centrum Nauki (National Science Centre)"],"pagination":["8981"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11487267"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["The Z-alkene geometry is prevalent in various chemical compounds, including numerous building blocks, fine chemicals, and natural products. Unfortunately, established Mo, W, and Ru Z-selective catalysts lose their selectivity at high temperatures required for industrial processes like reactive distillation, which limits their synthetic applications. To address this issue, we develop a catalyst capable of providing Z-alkenes with high selectivity under harsh conditions. Our research reveals a dithiolate ligand that, stabilised by resonance, delivers high selectivity at temperatures up to 150 °C in concentrated mixtures. This distinguishes the dithioquinoxaline complex from existing Z-selective catalysts. Notably, this trait does not compromise the new catalyst's usability under classical co"],"journal":["Nature communications"],"pubmed_title":["Preserving precise choreography of bonds in Z-stereoretentive olefin metathesis by using quinoxaline-2,3-dithiolate ligand."],"pmcid":["PMC11487267"],"funding_grant_id":["UMO-2019/33/B/ST4/00874"],"pubmed_authors":["Kajetanowicz A","Nadirova M","Guschlbauer J","Brotons-Rufes A","Grzesinski L","Poater A","Grela K"],"additional_accession":[]},"is_claimable":false,"name":"Preserving precise choreography of bonds in Z-stereoretentive olefin metathesis by using quinoxaline-2,3-dithiolate ligand.","description":"The Z-alkene geometry is prevalent in various chemical compounds, including numerous building blocks, fine chemicals, and natural products. Unfortunately, established Mo, W, and Ru Z-selective catalysts lose their selectivity at high temperatures required for industrial processes like reactive distillation, which limits their synthetic applications. To address this issue, we develop a catalyst capable of providing Z-alkenes with high selectivity under harsh conditions. Our research reveals a dithiolate ligand that, stabilised by resonance, delivers high selectivity at temperatures up to 150 °C in concentrated mixtures. This distinguishes the dithioquinoxaline complex from existing Z-selective catalysts. Notably, this trait does not compromise the new catalyst's usability under classical co","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-18T13:08:32.758Z","creation":"2025-04-06T22:41:04.322Z"},"accession":"S-EPMC11487267","cross_references":{"pubmed":["39420186"],"doi":["10.1038/s41467-024-52876-4"]}}