{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(5)"],"submitter":["Tonn JN"],"pubmed_abstract":["Caffeic acid is a polyphenol of critical importance in plants, involved in a variety of physiological processes including lignin formation, cellular growth, stress response, and external signaling. This small molecule also acts as a powerful antioxidant and thus has therapeutic potential for a variety of health conditions. Traditional methods of detecting caffeic acid lack appropriate temporal resolution to monitor real time concentration changes on a subsecond time scale with nM detection limits. Here we report on the first usage of fast-scan cyclic voltammetry with carbon fiber microelectrodes for the detection of caffeic acid. Through the use of flow injection analysis, the optimal waveform for its detection under acidic conditions at a scan rate of 400 V/s was determined to be sawtooth"],"journal":["ACS measurement science au"],"pagination":["534-545"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11487675"],"repository":["biostudies-literature"],"pubmed_title":["Waveform Optimization for the <i>In Vitro</i> Detection of Caffeic Acid by Fast-Scan Cyclic Voltammetry."],"pmcid":["PMC11487675"],"pubmed_authors":["Tonn JN","Keithley RB"],"additional_accession":[]},"is_claimable":false,"name":"Waveform Optimization for the <i>In Vitro</i> Detection of Caffeic Acid by Fast-Scan Cyclic Voltammetry.","description":"Caffeic acid is a polyphenol of critical importance in plants, involved in a variety of physiological processes including lignin formation, cellular growth, stress response, and external signaling. This small molecule also acts as a powerful antioxidant and thus has therapeutic potential for a variety of health conditions. Traditional methods of detecting caffeic acid lack appropriate temporal resolution to monitor real time concentration changes on a subsecond time scale with nM detection limits. Here we report on the first usage of fast-scan cyclic voltammetry with carbon fiber microelectrodes for the detection of caffeic acid. Through the use of flow injection analysis, the optimal waveform for its detection under acidic conditions at a scan rate of 400 V/s was determined to be sawtooth","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-04T19:45:59.352Z","creation":"2025-04-04T19:45:59.352Z"},"accession":"S-EPMC11487675","cross_references":{"pubmed":["39430967"],"doi":["10.1021/acsmeasuresciau.4c00029"]}}