{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Davidson HR"],"funding":["National Institute of Allergy and Infectious Diseases","Intramural NIH HHS","National Human Genome Research Institute"],"pagination":["117303"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11490359"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["360"],"pubmed_abstract":["Advances within the new genetics expand our understanding of the scope and presentation of inherited conditions, particularly to include incompletely penetrant and variably expressive conditions. These features can complicate patients' reproductive and family planning processes, in part because they expand the possibilities of life with an inherited condition. Despite many inquiries into reproductive planning with an inherited condition, accounts of experiential knowledge and reproductive planning fail to adequately describe the uncertainties experienced by people living with incompletely penetrant and variably expressive conditions. To address this gap, we conducted a qualitative, cross-sectional study using assemblage theory to characterize the impacts of experiential knowledge on reprod"],"journal":["Social science & medicine (1982)"],"pubmed_title":["Renegotiation, uncertainty, imagination: Assemblage perspectives on reproductive and family planning with an Inborn Error of immunity."],"pmcid":["PMC11490359"],"funding_grant_id":["Z01 AI000647"],"pubmed_authors":["Similuk M","Owczarzak J","Davidson HR","Jamal L","Mueller R"],"additional_accession":[]},"is_claimable":false,"name":"Renegotiation, uncertainty, imagination: Assemblage perspectives on reproductive and family planning with an Inborn Error of immunity.","description":"Advances within the new genetics expand our understanding of the scope and presentation of inherited conditions, particularly to include incompletely penetrant and variably expressive conditions. These features can complicate patients' reproductive and family planning processes, in part because they expand the possibilities of life with an inherited condition. Despite many inquiries into reproductive planning with an inherited condition, accounts of experiential knowledge and reproductive planning fail to adequately describe the uncertainties experienced by people living with incompletely penetrant and variably expressive conditions. To address this gap, we conducted a qualitative, cross-sectional study using assemblage theory to characterize the impacts of experiential knowledge on reprod","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-05T09:29:57.289Z","creation":"2026-05-15T03:12:20.229Z"},"accession":"S-EPMC11490359","cross_references":{"pubmed":["39265231"],"doi":["10.1016/j.socscimed.2024.117303"]}}