{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(1)"],"submitter":["Feng C"],"pubmed_abstract":["Direct photocatalytic conversion of methane to value-added C<sub>1</sub> oxygenate with O<sub>2</sub> is of great interest but presents a significant challenge in achieving highly selective product formation. Herein, a general strategy for the construction of copper single-atom catalysts with a well-defined coordination microenvironment is developed on the basis of metal-organic framework for selective photo-oxidation of CH<sub>4</sub> to HCHO. We propose the directional activation of O<sub>2</sub> on the mono-copper site breaks the original equilibrium and tilts the balance of radical formation almost completely toward •OOH. The synchronously generated •OOH and •CH<sub>3</sub> radicals rapidly combine to form HCHO while inhibiting competing reactions, thus resulting in ultra-highly select"],"journal":["Nature communications"],"pagination":["9088"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11494074"],"repository":["biostudies-literature"],"pubmed_title":["Optimizing the reaction pathway of methane photo-oxidation over single copper sites."],"pmcid":["PMC11494074"],"pubmed_authors":["Xia L","Luo J","Zhu Y","Rueping M","Wang S","Ren Y","Zhang H","Hu M","Han Y","Zou C","Zuo S","Feng C"],"additional_accession":[]},"is_claimable":false,"name":"Optimizing the reaction pathway of methane photo-oxidation over single copper sites.","description":"Direct photocatalytic conversion of methane to value-added C<sub>1</sub> oxygenate with O<sub>2</sub> is of great interest but presents a significant challenge in achieving highly selective product formation. Herein, a general strategy for the construction of copper single-atom catalysts with a well-defined coordination microenvironment is developed on the basis of metal-organic framework for selective photo-oxidation of CH<sub>4</sub> to HCHO. We propose the directional activation of O<sub>2</sub> on the mono-copper site breaks the original equilibrium and tilts the balance of radical formation almost completely toward •OOH. The synchronously generated •OOH and •CH<sub>3</sub> radicals rapidly combine to form HCHO while inhibiting competing reactions, thus resulting in ultra-highly select","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-04T14:37:10.662Z","creation":"2025-04-04T14:37:10.662Z"},"accession":"S-EPMC11494074","cross_references":{"pubmed":["39433749"],"doi":["10.1038/s41467-024-53483-z"]}}