{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(9)"],"submitter":["Mansur A"],"pubmed_abstract":["<h4>Background</h4>Primary lung signet-ring cell carcinoma (LSRCC) is a rare form of aggressive lung cancer whose clinical features remain inadequately discerned. The objective of this study was to evaluate the clinicopathological characteristics and independent prognostic factors of primary LSRCC.<h4>Methods</h4>Overall survival (OS) of patients with LSRCC, lung adenocarcinoma (LAC), and lung mucinous adenocarcinoma (LMAC) in the National Cancer Database from 2004 to 2018 was evaluated using Kaplan-Meier and multivariable Cox proportional hazards modeling. Independent prognostic indicators for patients with LSRCC were determined using multivariable Cox proportional hazards analysis.<h4>Results</h4>A total of 1,705 LSRCC, 504,006 LAC, and 15,883 LMAC patients were included in our analysis."],"journal":["Journal of thoracic disease"],"pagination":["5899-5908"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11494572"],"repository":["biostudies-literature"],"pubmed_title":["Primary lung signet-ring cell carcinoma: a national analysis."],"pmcid":["PMC11494572"],"pubmed_authors":["Mansur A","Saleem Z","Potter AL","Senthil P","Yang CJ","Mathey-Andrews C"],"additional_accession":[]},"is_claimable":false,"name":"Primary lung signet-ring cell carcinoma: a national analysis.","description":"<h4>Background</h4>Primary lung signet-ring cell carcinoma (LSRCC) is a rare form of aggressive lung cancer whose clinical features remain inadequately discerned. The objective of this study was to evaluate the clinicopathological characteristics and independent prognostic factors of primary LSRCC.<h4>Methods</h4>Overall survival (OS) of patients with LSRCC, lung adenocarcinoma (LAC), and lung mucinous adenocarcinoma (LMAC) in the National Cancer Database from 2004 to 2018 was evaluated using Kaplan-Meier and multivariable Cox proportional hazards modeling. Independent prognostic indicators for patients with LSRCC were determined using multivariable Cox proportional hazards analysis.<h4>Results</h4>A total of 1,705 LSRCC, 504,006 LAC, and 15,883 LMAC patients were included in our analysis.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2025-04-03T23:51:53.506Z","creation":"2025-04-03T23:51:53.506Z"},"accession":"S-EPMC11494572","cross_references":{"pubmed":["39444872"],"doi":["10.21037/jtd-24-102"]}}