biostudies-literatureZhao YNational Natural Science Foundation of China146https://www.ebi.ac.uk/biostudies/studies/S-EPMC11494863biostudies-literatureUnknown19(1)<h4>Background</h4>This study aims to assess the clinical efficacy of elective neck irradiation (ENI) in patients with esthesineuroblastoma (ENB), a rare malignant neoplasm, who are clinically node-negative.<h4>Methods</h4>We conducted a retrospective analysis of 178 patients newly diagnosed with ENB at our institution between 2009 and 2021. Propensity score matching (PSM) was employed to compare node-negative patients treated with and without ENI. We extensively examined survival outcomes and treatment failure.<h4>Results</h4>Of the 178 participants, 149 (83.7%) were lymph node-negative and staged in Modified Kadish A-C. 96 patients underwent ENI treatment, while 53 did not. At baseline, patients who received ENI differed from those who did not in terms of radiotherapy technique, staging,Radiation oncology (London, England)The value of elective neck irradiation in management of esthesioneuroblastoma: a retrospective study based on propensity score matching.PMC1149486382303420Yan LZhu YLi RWang XZhao YfalseThe value of elective neck irradiation in management of esthesioneuroblastoma: a retrospective study based on propensity score matching.<h4>Background</h4>This study aims to assess the clinical efficacy of elective neck irradiation (ENI) in patients with esthesineuroblastoma (ENB), a rare malignant neoplasm, who are clinically node-negative.<h4>Methods</h4>We conducted a retrospective analysis of 178 patients newly diagnosed with ENB at our institution between 2009 and 2021. Propensity score matching (PSM) was employed to compare node-negative patients treated with and without ENI. We extensively examined survival outcomes and treatment failure.<h4>Results</h4>Of the 178 participants, 149 (83.7%) were lymph node-negative and staged in Modified Kadish A-C. 96 patients underwent ENI treatment, while 53 did not. At baseline, patients who received ENI differed from those who did not in terms of radiotherapy technique, staging,2024-01-01T00:00:00Z2024 Oct2025-04-04T19:45:25.146Z2025-04-04T19:45:25.146ZS-EPMC114948633943415510.1186/s13014-024-02539-x