{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Appel KS"],"funding":["Johann Wolfgang Goethe-Universität, Frankfurt am Main","German Federal Ministry of Education and Research (BMBF) Network of University Medicine 2.0: \"NUM 2.0\"","German Federal Ministry of Education and Research (BMBF) Network of University Medicine 2.0: “NUM 2.0""],"pagination":["1813-1829"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11499320"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["52(5)"],"pubmed_abstract":["Purpose
The objective examination of the Post-COVID syndrome (PCS) remains difficult due to heterogeneous definitions and clinical phenotypes. The aim of the study was to verify the functionality and correlates of a recently developed PCS score.Methods
The PCS score was applied to the prospective, multi-center cross-sectoral cohort (in- and outpatients with SARS-CoV-2 infection) of the \"National Pandemic Cohort Network (NAPKON, Germany)\". Symptom assessment and patient-reported outcome measure questionnaires were analyzed at 3 and 12 months (3/12MFU) after diagnosis. Scores indicative of PCS severity were compared and correlated to demographic and clinical characteristics as well as quality of life (QoL, EQ-5D-5L).Results
Six hundred three patients (mean 54.0 years,"],"journal":["Infection"],"pubmed_title":["Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON)."],"pmcid":["PMC11499320"],"funding_grant_id":["Grant No. 01KX2121"],"pubmed_authors":["Knopp L","Heuschmann P","Heuschmann PU","Meybohm P","Klinsing S","Nussbeck SY","Schreiber S","Haas K","Gopel S","Willam C","Arlt A","Tausche K","Addo M","Weinert N","Lorbeer R","Krawczak M","Maasjosthusmann P","Konik M","Laumerich B","Herrmann J","Hagen M","Weismantel C","Roemmele C","Prenzel R","Brinkmann F","Bercker S","Schulze P","Schulze N","Stahl D","Hanses F","Haertel C","Tamminga T","Scheer C","Koerner M","Krug N","Hansch S","Zeller T","Polidori MC","Lorenz-Depiereux B","Sikdar S","Kienzle K","Jensen BO","Bellinghausen C","Zeh S","Berner R","Marx N","Wallner S","Isberner N","Gruenewaldt A","Luedde T","Kobbe R","Pape D","Blaschke S","Pape C","Erber J","Griesinger F","Hettich-Damm N","Malek N","Dreher M","Baber R","Chaplinskaya I","Altmann H","Brochhausen-Delius C","Gunther K","Stellbrink C","Mueller SD","Otte M","Nurnberger C","Muzalyova A","Krefting D","Timm J","Hamprecht A","Wilms C","Torres Reyes C","Vollenberg R","Engelmann M","Koch T","Brohl I","Miljukov O","Vehreschild JJ","Leppkes M","Hamelmann E","Steinmann E","Brochhagen L","Schaller J","Kujat C","Schuette C","Wagner P","Prokosch HU","Santibanez-Santana M","Fiessler C","Schunk D","Haug F","Paluschinski M","Elsner C","Haug J","Hellwig K","Khodamoradi Y","Petersen J","Nowacki T","Toepfner N","Spinner C","Ruwe M","Oberlaender M","Kluge A","Burkhardt R","Illig T","Kerinn M","Spieth P","Niedermair T","Witzke O","Doerr M","Heyder R","Krawczyk A","Hanß S","Muna A","Seele K","Wolf K","Wolf L","Witzenrath M","Nauck M","Feldt T","Groh A","Bunk S","NAPKON Study Group","Maerkl B","Schuster P","Jarczak D","Krist L","Kraska D","Meier JA","Kluge S","Rainers M","Brechtel M","Hafke A","Weigl M","Lieb J","Seibel K","Finke C","Wirtz H","Petereit S","Haag O","Sauer G","Boeckel G","Bitzer M","Lieb W","Mitrov L","Dashti Y","Pereira JPV","Michler T","Hoffmann W","Hopff SM","Scherer M","Arendt C","Barkey W","Reinacher-Schick A","Heidenreich H","Tepasse PR","Silberbaur I","Dolff S","Frey A","Gambichler T","Plagge M","Fiedler K","Liese J","Frantz S","Trauner F","Dashti H","Malfertheiner M","Mueller L","Langer A","Dressen S","Piasta N","Vogl T","Tessmer C","Guenther U","Friedrichs A","Keitel V","Meinhardt K","Neurath MF","Lee C","Meinhardt C","Vetter M","Stecher M","Cremer S","Tebbe JJ","Lindemann D","Schneider J","Reese JP","Butzmann J","Jiru-Hillmann S","Schaefer C","Madel RJ","Feustel M","Petersmann A","Schaefer E","Rohde G","Juergens K","Kremer AE","Luecke T","Kraus T","Hermes A","Ronnefarth M","Kraus M","Schmidt J","Kohls M","Schattschneider M","Schmidt S","Bader S","Rupp J","Messmann H","de Miranda SMN","Bahls T","Struemper C","Bonin SV","Bahmer T","Schlesner C","Mueller-Wieland D","Brueggemann Y","Lemhofer C","Hornberg C","Mang J","Mahrhofer H","Vehreschild M","Rosenberger P","Deckert J","Herold S","Almahfoud M","Becker K","Kaeding N","Schmid J","Lutterbeck M","Hermanns G","Dahl E","Engels ALF","Cleef S","Kulamadayil-Heidenreich NSA","Killer A","Valentin H","Fricke J","Schmidt WE","Voit F","Wipperfuerth J","Appel KS","Haeberle H","Schoneberg A","Fricke L","Alsaad K","Winter C","Schmidbauer L","Forster C","Buechner N","Laugwitz M","Lehnert K","Geisler R","Fuchs A"],"additional_accession":[]},"is_claimable":false,"name":"Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON).","description":"Purpose
The objective examination of the Post-COVID syndrome (PCS) remains difficult due to heterogeneous definitions and clinical phenotypes. The aim of the study was to verify the functionality and correlates of a recently developed PCS score.Methods
The PCS score was applied to the prospective, multi-center cross-sectoral cohort (in- and outpatients with SARS-CoV-2 infection) of the \"National Pandemic Cohort Network (NAPKON, Germany)\". Symptom assessment and patient-reported outcome measure questionnaires were analyzed at 3 and 12 months (3/12MFU) after diagnosis. Scores indicative of PCS severity were compared and correlated to demographic and clinical characteristics as well as quality of life (QoL, EQ-5D-5L).Results
Six hundred three patients (mean 54.0 years,","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-06-03T00:42:41.569Z","creation":"2025-04-04T00:21:30.052Z"},"accession":"S-EPMC11499320","cross_references":{"pubmed":["38587752"],"doi":["10.1007/s15010-024-02226-9"]}}