biostudies-literatureUnknown12(10)Trejo-Trejo MNo consensus exists on whether acute aerobic exercise alters the glomerular filtration rate in older adults.<h4>Objective</h4>To assess the immediate effects of three aerobic exercise intensities on the estimated glomerular filtration rate (eGFR) in healthy, sedentary older adults.<h4>Methods</h4>Eighteen healthy, sedentary older adults (ten men and eight women) voluntarily participated in this study. The participants underwent three standardized aerobic exercise tests (100%, 80%, and 60% of the maximal heart rate) on a bicycle ergometer. Blood samples were collected to determine cholesterol, triacylglycerols, glucose, serum creatinine (Cr), Cystatin C (CysC) concentrations, and eGFR.<h4>Results</h4>eGFR and serum concentrations of Cr and CysC were not modified at any exercise intensity. TDiseases (Basel, Switzerland)249https://www.ebi.ac.uk/biostudies/studies/S-EPMC11507922biostudies-literatureAcute Effect of Three Aerobic Exercise Intensities on Glomerular Filtration Rate in Healthy Older Adults.PMC11507922Gomez-Miranda LMTrejo-Trejo MRamos-Jimenez AfalseAcute Effect of Three Aerobic Exercise Intensities on Glomerular Filtration Rate in Healthy Older Adults.No consensus exists on whether acute aerobic exercise alters the glomerular filtration rate in older adults.<h4>Objective</h4>To assess the immediate effects of three aerobic exercise intensities on the estimated glomerular filtration rate (eGFR) in healthy, sedentary older adults.<h4>Methods</h4>Eighteen healthy, sedentary older adults (ten men and eight women) voluntarily participated in this study. The participants underwent three standardized aerobic exercise tests (100%, 80%, and 60% of the maximal heart rate) on a bicycle ergometer. Blood samples were collected to determine cholesterol, triacylglycerols, glucose, serum creatinine (Cr), Cystatin C (CysC) concentrations, and eGFR.<h4>Results</h4>eGFR and serum concentrations of Cr and CysC were not modified at any exercise intensity. T2024-01-01T00:00:00Z2024 Oct2025-04-26T00:18:16.175Z2025-04-06T09:40:42.033ZS-EPMC115079223945249210.3390/diseases12100249