biostudies-literatureMuniz-Santos RCoordenação de Aperfeicoamento de Pessoal de Nível SuperiorMerck Sigma AldrichFinanciadora de Estudos e ProjetosWaters CorporationIan Lawson van Toch FundUniversity of TorontoNatural Sciences Research CouncilIBMCanada Foundation for InnovationUniversidade Federal do Estado do Rio de JaneiroNational Council for Scientific and Technological DevelopmentOntario Research FundFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro3538https://www.ebi.ac.uk/biostudies/studies/S-EPMC11510449biostudies-literatureUnknown16(20)<h4>Background</h4>Exercise can be used as a model to understand immunometabolism. Biological data on elite athletes are limited, especially for female athletes, including relevant data on acute-phase proteins and amino acid metabolism.<h4>Methods</h4>We analyzed acute-phase proteins and amino acids collected at South American, Pan-American, and Olympic Games for 16 Olympic sports. We compared female and male elite athletes (447 vs. 990 samples) across four states (fasting, pre-exercise, post-exercise, and resting) to understand sex-specific immunometabolic responses in elite athletes.<h4>Results</h4>Considering all states and sports, we found that elite female athletes exhibited higher concentrations of C-reactive protein, lipopolysaccharide-binding protein, myeloperoxidase, haptoglobin, NutrientsSportomics Analyses of the Exercise-Induced Impact on Amino Acid Metabolism and Acute-Phase Protein Kinetics in Female Olympic Athletes.PMC11510449NACFI #225404, #30865NSERC #203475RDI #34876, RE010-020Falcao JMartin LJurisica IMuniz-Santos RBassini AChandran VPrado ECameron LCfalseSportomics Analyses of the Exercise-Induced Impact on Amino Acid Metabolism and Acute-Phase Protein Kinetics in Female Olympic Athletes.<h4>Background</h4>Exercise can be used as a model to understand immunometabolism. Biological data on elite athletes are limited, especially for female athletes, including relevant data on acute-phase proteins and amino acid metabolism.<h4>Methods</h4>We analyzed acute-phase proteins and amino acids collected at South American, Pan-American, and Olympic Games for 16 Olympic sports. We compared female and male elite athletes (447 vs. 990 samples) across four states (fasting, pre-exercise, post-exercise, and resting) to understand sex-specific immunometabolic responses in elite athletes.<h4>Results</h4>Considering all states and sports, we found that elite female athletes exhibited higher concentrations of C-reactive protein, lipopolysaccharide-binding protein, myeloperoxidase, haptoglobin, 2024-01-01T00:00:00Z2024 Oct2025-04-04T02:22:53.944Z2025-04-04T02:22:53.944ZS-EPMC115104493945853210.3390/nu16203538