{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(4)"],"submitter":["Kennedy E"],"pubmed_abstract":["<h4>Objective</h4>To provide a review of the science and applicability of current multi-cancer early detection (MCED) tests for otolaryngologists.<h4>Data sources</h4>PubMed, clinicaltrials.gov, company websites.<h4>Review methods</h4>Using PRISMA methodology, primary literature regarding MCED tests was queried from April 26 to May 12, 2024 using MCED search terms. Ongoing clinical trials incorporating MCED screens were identified via the National Institutes of Health clinicaltrials.gov website. Company websites for available or upcoming MCED tests were reviewed.<h4>Conclusion</h4>Long-term robust data regarding the performance characteristics, effects on clinical outcomes, and cost-utility of MCED tests for head and neck cancer are currently lacking. Otolaryngologists should be aware of t"],"journal":["OTO open"],"pagination":["e70040"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11512445"],"repository":["biostudies-literature"],"pubmed_title":["Multicancer Early Detection Tests: A State-of-the-Art Review for Otolaryngologists."],"pmcid":["PMC11512445"],"pubmed_authors":["Kennedy E","Farlow JL","Durm G"],"additional_accession":[]},"is_claimable":false,"name":"Multicancer Early Detection Tests: A State-of-the-Art Review for Otolaryngologists.","description":"<h4>Objective</h4>To provide a review of the science and applicability of current multi-cancer early detection (MCED) tests for otolaryngologists.<h4>Data sources</h4>PubMed, clinicaltrials.gov, company websites.<h4>Review methods</h4>Using PRISMA methodology, primary literature regarding MCED tests was queried from April 26 to May 12, 2024 using MCED search terms. Ongoing clinical trials incorporating MCED screens were identified via the National Institutes of Health clinicaltrials.gov website. Company websites for available or upcoming MCED tests were reviewed.<h4>Conclusion</h4>Long-term robust data regarding the performance characteristics, effects on clinical outcomes, and cost-utility of MCED tests for head and neck cancer are currently lacking. Otolaryngologists should be aware of t","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct-Dec","modification":"2026-07-06T03:12:38.841Z","creation":"2025-04-06T14:22:58.907Z"},"accession":"S-EPMC11512445","cross_references":{"pubmed":["39463807"],"doi":["10.1002/oto2.70040"]}}