biostudies-literatureUnknown12Li M<h4>Background</h4>Data on the association between the plain ropivacaine dose and maternal hypotension during cesarean delivery are limited. Thus, this study aimed to explore this association.<h4>Methods</h4>This retrospective study included patients undergoing cesarean sections under spinal or combined spinal-epidural anesthesia with plain ropivacaine at The First Hospital of Fuyang, Hangzhou, China, between 2018 and 2022. Data were obtained from the anesthesia information management system. Liner trend tests were used to distinguish the linear relationship between spinal hypotension and the plain ropivacaine dose, and receiver operating characteristic curves were used to calculate the dose threshold. Logistic regression was used to adjust for confounders. Sensitivity analyses were perforPeerJe18398https://www.ebi.ac.uk/biostudies/studies/S-EPMC11512552biostudies-literatureAssociation between plain ropivacaine dose and spinal hypotension for cesarean delivery: a retrospective study.PMC11512552Fang XXie GChu LLi MfalseAssociation between plain ropivacaine dose and spinal hypotension for cesarean delivery: a retrospective study.<h4>Background</h4>Data on the association between the plain ropivacaine dose and maternal hypotension during cesarean delivery are limited. Thus, this study aimed to explore this association.<h4>Methods</h4>This retrospective study included patients undergoing cesarean sections under spinal or combined spinal-epidural anesthesia with plain ropivacaine at The First Hospital of Fuyang, Hangzhou, China, between 2018 and 2022. Data were obtained from the anesthesia information management system. Liner trend tests were used to distinguish the linear relationship between spinal hypotension and the plain ropivacaine dose, and receiver operating characteristic curves were used to calculate the dose threshold. Logistic regression was used to adjust for confounders. Sensitivity analyses were perfor2024-01-01T00:00:00Z20242026-07-15T14:52:45.654Z2026-07-06T03:09:24.437ZS-EPMC115125523946515410.7717/peerj.18398