{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Slavinska A"],"pubmed_abstract":["<h4>Introduction</h4><i>Neisseria meningitidis</i> is a gram-negative bacterium responsible for life-threatening invasive infections known as invasive meningococcal disease and is associated with high fatality rates and serious lifelong disabilities among survivors.<h4>Methods</h4>This study aimed to characterize <i>N. meningitidis</i> isolates cultured from blood and cerebrospinal fluid collected between 2009 and 2021 in Lithuania, assess their genomic relationships with European strains, and evaluate the possibility of using a cost-effective method for strain characterization, thus improving the national molecular surveillance of invasive meningococcal disease. In total, 321 <i>N. meningitidis</i> isolates were collected and analyzed using multilocus restriction typing (MLRT). Amplificat"],"journal":["Frontiers in cellular and infection microbiology"],"pagination":["1432197"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11513629"],"repository":["biostudies-literature"],"pubmed_title":["Genetic characterization of <i>Neisseria meningitidis</i> isolates recovered from patients with invasive meningococcal disease in Lithuania."],"pmcid":["PMC11513629"],"pubmed_authors":["Tamosiuniene K","Slavinska A","Vizuje G","Kuisiene N","Kirkliauskiene A","Siedlecki P","Petrutiene A","Kowalczyk M","Bikulciene J"],"additional_accession":[]},"is_claimable":false,"name":"Genetic characterization of <i>Neisseria meningitidis</i> isolates recovered from patients with invasive meningococcal disease in Lithuania.","description":"<h4>Introduction</h4><i>Neisseria meningitidis</i> is a gram-negative bacterium responsible for life-threatening invasive infections known as invasive meningococcal disease and is associated with high fatality rates and serious lifelong disabilities among survivors.<h4>Methods</h4>This study aimed to characterize <i>N. meningitidis</i> isolates cultured from blood and cerebrospinal fluid collected between 2009 and 2021 in Lithuania, assess their genomic relationships with European strains, and evaluate the possibility of using a cost-effective method for strain characterization, thus improving the national molecular surveillance of invasive meningococcal disease. In total, 321 <i>N. meningitidis</i> isolates were collected and analyzed using multilocus restriction typing (MLRT). Amplificat","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-07-15T17:42:20.156Z","creation":"2025-04-04T00:29:38.39Z"},"accession":"S-EPMC11513629","cross_references":{"pubmed":["39469455"],"doi":["10.3389/fcimb.2024.1432197"]}}