biostudies-literatureUnknown101Ghadimi N<h4>Background</h4>With the rising burden of cardiovascular disease (CVD) and the need for cost-effective interventions, evaluating the economic implications of Evolocumab becomes crucial.<h4>Objectives</h4>This study aimed to systematically review and evaluate the cost-effectiveness of Evolocumab in adults at risk of CVD.<h4>Methods</h4>We performed an extensive search in Cochrane Library, EMBASE, PubMed, ProQuest, and Web of Science. The reference lists of chosen literature reviews were also examined to find suitable cost-effectiveness analyses (CEAs) of Evolocumab in patients with CVD published until March 2023. The Consolidated Health Economic Evaluation Reporting Standards statement (CHEERS) was used to assess the reporting quality. Cost-related findings were adjusted to reflect 2023 Current therapeutic research, clinical and experimental100758https://www.ebi.ac.uk/biostudies/studies/S-EPMC11513655biostudies-literatureCost-effectiveness of Evolocumab in Cardiovascular Disease: A Systematic Review.PMC11513655Goharimehr MKhodamorzideh DKaveh SShabaninejad HDaroudi RGhadimi NfalseCost-effectiveness of Evolocumab in Cardiovascular Disease: A Systematic Review.<h4>Background</h4>With the rising burden of cardiovascular disease (CVD) and the need for cost-effective interventions, evaluating the economic implications of Evolocumab becomes crucial.<h4>Objectives</h4>This study aimed to systematically review and evaluate the cost-effectiveness of Evolocumab in adults at risk of CVD.<h4>Methods</h4>We performed an extensive search in Cochrane Library, EMBASE, PubMed, ProQuest, and Web of Science. The reference lists of chosen literature reviews were also examined to find suitable cost-effectiveness analyses (CEAs) of Evolocumab in patients with CVD published until March 2023. The Consolidated Health Economic Evaluation Reporting Standards statement (CHEERS) was used to assess the reporting quality. Cost-related findings were adjusted to reflect 2023 2024-01-01T00:00:00Z20242026-06-02T04:56:51.337Z2025-04-04T00:29:41.354ZS-EPMC115136553946909210.1016/j.curtheres.2024.100758