{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kong X"],"funding":["Strategic Priority Research Program of the Chinese Academy of Sciences","Jiangsu Agriculture Science and Technology Innovation Fund (JASTIF)","Jiangsu Agriculture Science and Technology Innovation Fund","National Natural Science Foundation of China","Strategic Priority Research Program of the Chinese Academy of Sciences (CAS)","Natural Science Foundation of Jiangsu Province"],"pagination":["1006"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11514971"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Background</h4>The deep-sea cold seep zone is characterized by high pressure, low temperature, darkness, and oligotrophy. Vesicomyidae clams are the dominant species within this environment, often forming symbiotic relationships with chemosynthetic microbes. Understanding the mechanisms by which Vesicomyidae clams adapt to the cold seep environment is significant. Acetylation modification of lysine is known to play a crucial role in various metabolic processes. Consequently, investigating the role of lysine acetylation in the adaptation of Vesicomyidae clams to deep-sea environments is worthwhile. So, a comparative study of lysine acetylation in cold seep clam Archivesica marissinica and shallow water shellfish Ruditapes philippinarum was conducted.<h4>Results</h4>A total of 539 acetyl"],"journal":["BMC genomics"],"pubmed_title":["Comparative study of lysine acetylation in Vesicomyidae clam Archivesica marissinica and the manila clam Ruditapes philippinarum: adaptation mechanisms in cold seep environments."],"pmcid":["PMC11514971"],"funding_grant_id":["CX(22)2032","BK20210927","XDA22050303","42376139"],"pubmed_authors":["Zhi Y","Song M","Zhang H","Cai Y","Wang W","Chen S","Shen X","Kong X"],"additional_accession":[]},"is_claimable":false,"name":"Comparative study of lysine acetylation in Vesicomyidae clam Archivesica marissinica and the manila clam Ruditapes philippinarum: adaptation mechanisms in cold seep environments.","description":"<h4>Background</h4>The deep-sea cold seep zone is characterized by high pressure, low temperature, darkness, and oligotrophy. Vesicomyidae clams are the dominant species within this environment, often forming symbiotic relationships with chemosynthetic microbes. Understanding the mechanisms by which Vesicomyidae clams adapt to the cold seep environment is significant. Acetylation modification of lysine is known to play a crucial role in various metabolic processes. Consequently, investigating the role of lysine acetylation in the adaptation of Vesicomyidae clams to deep-sea environments is worthwhile. So, a comparative study of lysine acetylation in cold seep clam Archivesica marissinica and shallow water shellfish Ruditapes philippinarum was conducted.<h4>Results</h4>A total of 539 acetyl","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-07-07T03:15:17.956Z","creation":"2025-04-04T00:29:43.079Z"},"accession":"S-EPMC11514971","cross_references":{"pubmed":["39465380"],"doi":["10.1186/s12864-024-10916-9"]}}