{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sim EJ"],"funding":["National Research Foundation of Korea","Korea Research Institute of Bioscience and Biotechnology"],"pagination":["290"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11515633"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>Microalgae are potential sustainable resources for the production of value-added chemicals that can be used as biofuels, pharmaceuticals, and nutritional supplements. Arachidonic acid (ARA), a omega-6 fatty acid, plays a crucial role in infant development and immune response, and can be used in cosmetics and pharmaceuticals. Demand for industrial-scale ARA production is continuously increasing because of its broad applicability. To address this demand, there has been a significant shift towards microorganism-based ARA production. To accelerate large-scale ARA production, it is crucial to select suitable strains and establish optimal culture conditions.<h4>Results</h4>Here, we isolated a novel microalga Lobosphaera incisa CFRC-1, a valuable strain that holds promise as a "],"journal":["Microbial cell factories"],"pubmed_title":["High-throughput optimization of organic carbon provision strategies enables enhanced arachidonic acid production in novel microalgae."],"pmcid":["PMC11515633"],"funding_grant_id":["KGM5252423","2021R1C1C1003425","RS-2024-00351663"],"pubmed_authors":["Shin BS","Lee YR","Choi DY","Kim G","Sim EJ","Park SB","Choi HI","Kim HS","Cho DH","Lee YJ","Yun JH"],"additional_accession":[]},"is_claimable":false,"name":"High-throughput optimization of organic carbon provision strategies enables enhanced arachidonic acid production in novel microalgae.","description":"<h4>Background</h4>Microalgae are potential sustainable resources for the production of value-added chemicals that can be used as biofuels, pharmaceuticals, and nutritional supplements. Arachidonic acid (ARA), a omega-6 fatty acid, plays a crucial role in infant development and immune response, and can be used in cosmetics and pharmaceuticals. Demand for industrial-scale ARA production is continuously increasing because of its broad applicability. To address this demand, there has been a significant shift towards microorganism-based ARA production. To accelerate large-scale ARA production, it is crucial to select suitable strains and establish optimal culture conditions.<h4>Results</h4>Here, we isolated a novel microalga Lobosphaera incisa CFRC-1, a valuable strain that holds promise as a ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-07-15T14:44:01Z","creation":"2025-04-04T22:47:33.436Z"},"accession":"S-EPMC11515633","cross_references":{"pubmed":["39443949"],"doi":["10.1186/s12934-024-02560-5"]}}