biostudies-literatureSim EJNational Research Foundation of KoreaKorea Research Institute of Bioscience and Biotechnology290https://www.ebi.ac.uk/biostudies/studies/S-EPMC11515633biostudies-literatureUnknown23(1)<h4>Background</h4>Microalgae are potential sustainable resources for the production of value-added chemicals that can be used as biofuels, pharmaceuticals, and nutritional supplements. Arachidonic acid (ARA), a omega-6 fatty acid, plays a crucial role in infant development and immune response, and can be used in cosmetics and pharmaceuticals. Demand for industrial-scale ARA production is continuously increasing because of its broad applicability. To address this demand, there has been a significant shift towards microorganism-based ARA production. To accelerate large-scale ARA production, it is crucial to select suitable strains and establish optimal culture conditions.<h4>Results</h4>Here, we isolated a novel microalga Lobosphaera incisa CFRC-1, a valuable strain that holds promise as a Microbial cell factoriesHigh-throughput optimization of organic carbon provision strategies enables enhanced arachidonic acid production in novel microalgae.PMC11515633KGM52524232021R1C1C1003425RS-2024-00351663Shin BSLee YRChoi DYKim GSim EJPark SBChoi HIKim HSCho DHLee YJYun JHfalseHigh-throughput optimization of organic carbon provision strategies enables enhanced arachidonic acid production in novel microalgae.<h4>Background</h4>Microalgae are potential sustainable resources for the production of value-added chemicals that can be used as biofuels, pharmaceuticals, and nutritional supplements. Arachidonic acid (ARA), a omega-6 fatty acid, plays a crucial role in infant development and immune response, and can be used in cosmetics and pharmaceuticals. Demand for industrial-scale ARA production is continuously increasing because of its broad applicability. To address this demand, there has been a significant shift towards microorganism-based ARA production. To accelerate large-scale ARA production, it is crucial to select suitable strains and establish optimal culture conditions.<h4>Results</h4>Here, we isolated a novel microalga Lobosphaera incisa CFRC-1, a valuable strain that holds promise as a 2024-01-01T00:00:00Z2024 Oct2026-07-15T14:44:01Z2025-04-04T22:47:33.436ZS-EPMC115156333944394910.1186/s12934-024-02560-5