{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Akahori Y"],"funding":["Takeda Science Foundation","Japan Society for the Promotion of Science"],"pagination":["e0312500"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11515972"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(10)"],"pubmed_abstract":["Community-acquired pneumonia is caused primarily by bacterial infection. For years, antibiotic treatment has been the standard of care for patients with bacterial pneumonia, although the emergence of antimicrobial-resistant strains is recognized as a global health issue. The traditional herbal medicine Kampo has a long history of clinical use and is relatively safe in treating various diseases. However, the antimicrobial effects of Kampo products against pneumonia-causative bacteria remain largely uncharacterized. In this study, we investigated the bacteriological efficacy of 11 Kampo products against bacteria commonly associated with pneumonia. Sho-saiko-To (9), Sho-seiryu-To (19), Chikujo-untan-To (91) and Shin'i-seihai-To (104) inhibited the growth of S. pneumoniae serotype 3, a highly "],"journal":["PloS one"],"pubmed_title":["Antibacterial effects of Kampo products against pneumonia causative bacteria."],"pmcid":["PMC11515972"],"funding_grant_id":["21K15654"],"pubmed_authors":["Shizuno K","Akahori Y","Nagasawa M","Hashimoto Y"],"additional_accession":[]},"is_claimable":false,"name":"Antibacterial effects of Kampo products against pneumonia causative bacteria.","description":"Community-acquired pneumonia is caused primarily by bacterial infection. For years, antibiotic treatment has been the standard of care for patients with bacterial pneumonia, although the emergence of antimicrobial-resistant strains is recognized as a global health issue. The traditional herbal medicine Kampo has a long history of clinical use and is relatively safe in treating various diseases. However, the antimicrobial effects of Kampo products against pneumonia-causative bacteria remain largely uncharacterized. In this study, we investigated the bacteriological efficacy of 11 Kampo products against bacteria commonly associated with pneumonia. Sho-saiko-To (9), Sho-seiryu-To (19), Chikujo-untan-To (91) and Shin'i-seihai-To (104) inhibited the growth of S. pneumoniae serotype 3, a highly ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-07-15T14:44:15.738Z","creation":"2026-07-06T03:08:05.776Z"},"accession":"S-EPMC11515972","cross_references":{"pubmed":["39466752"],"doi":["10.1371/journal.pone.0312500"]}}