biostudies-literatureZhao SNHLBI NIH HHSthe Natural Science Basic Research Program of Shaanxi715https://www.ebi.ac.uk/biostudies/studies/S-EPMC11520185biostudies-literatureUnknown24(1)<h4>Objectives</h4>Sleep characteristics such as duration, continuity, and irregularity are associated with the risk of hypertension. This study aimed to investigate the association between sleep timing (including bedtime, wake-up time, and sleep midpoint) and the prevalence of hypertension.<h4>Methods</h4>Participants were selected from the Sleep Heart Health Study (n = 5504). Bedtime and wake-up times were assessed using sleep habit questionnaires. The sleep midpoint was calculated as the halfway point between the bedtime and wake-up time. Restricted cubic splines and logistic regression analyses were performed to explore the association between sleep timing and hypertension.<h4>Results</h4>A significant nonlinear association was observed between bedtime (P_overall<0.001; P<subBMC psychiatrySleep timing and the prevalence of hypertension in middle-aged and older populations: the sleep heart health study.PMC11520185U01 HL063463U01 HL053931U01 HL053941No. 2021JQ-395U01 HL053934U01 HL053916U01 HL053938R24 HL114473U01 HL053937U01 HL064360Zhao SWei SWang WYan BZhao JWu YfalseSleep timing and the prevalence of hypertension in middle-aged and older populations: the sleep heart health study.<h4>Objectives</h4>Sleep characteristics such as duration, continuity, and irregularity are associated with the risk of hypertension. This study aimed to investigate the association between sleep timing (including bedtime, wake-up time, and sleep midpoint) and the prevalence of hypertension.<h4>Methods</h4>Participants were selected from the Sleep Heart Health Study (n = 5504). Bedtime and wake-up times were assessed using sleep habit questionnaires. The sleep midpoint was calculated as the halfway point between the bedtime and wake-up time. Restricted cubic splines and logistic regression analyses were performed to explore the association between sleep timing and hypertension.<h4>Results</h4>A significant nonlinear association was observed between bedtime (P_overall<0.001; P<sub2024-01-01T00:00:00Z2024 Oct2026-06-02T04:59:39.789Z2025-04-04T00:27:40.014ZS-EPMC115201853943885610.1186/s12888-024-06174-4