{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Piedra HF"],"funding":["Fundación para el Fomento en Asturias de la Investigación Científica Aplicada y la Tecnología","Ministerio de Ciencia, Innovación y Universidades","Universidad de Oviedo"],"pubmed_abstract":["The first visible-light-induced protocol for the general preparation of alkenyl thiocyanates from alkenyl bromides is presented. The reaction is simple, proceeds under very mild conditions and demonstrates broad functional group tolerance. Additionally, a flow protocol was developed to enable efficient scale-up of alkenyl thiocyanate synthesis, further enhancing the practicality and value of the method. Importantly, these alkenyl thiocyanates serve as valuable building blocks for the construction of diverse families of sulfur-containing molecules through trifluoromethylations, cycloadditions, oxidations, and C-S or P-S bond forming reactions."],"journal":["Chemical science"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11523809"],"repository":["biostudies-literature"],"pubmed_title":["Visible-light-driven synthesis of alkenyl thiocyanates: novel building blocks for assembly of diverse sulfur-containing molecules."],"pmcid":["PMC11523809"],"funding_grant_id":["BP21/050","MCINN-23-PID2022-140635NB-I00","MCINN-24-RYC2022-035485-I","PAPI-23-GR-COM-04"],"pubmed_authors":["Plaza M","Piedra HF"],"additional_accession":[]},"is_claimable":false,"name":"Visible-light-driven synthesis of alkenyl thiocyanates: novel building blocks for assembly of diverse sulfur-containing molecules.","description":"The first visible-light-induced protocol for the general preparation of alkenyl thiocyanates from alkenyl bromides is presented. The reaction is simple, proceeds under very mild conditions and demonstrates broad functional group tolerance. Additionally, a flow protocol was developed to enable efficient scale-up of alkenyl thiocyanate synthesis, further enhancing the practicality and value of the method. Importantly, these alkenyl thiocyanates serve as valuable building blocks for the construction of diverse families of sulfur-containing molecules through trifluoromethylations, cycloadditions, oxidations, and C-S or P-S bond forming reactions.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-04T20:38:43.25Z","creation":"2025-04-04T20:38:43.25Z"},"accession":"S-EPMC11523809","cross_references":{"pubmed":["39483256"],"doi":["10.1039/d4sc06550f"]}}