biostudies-literatureUnknown16Xu W<h4>Aim</h4>To explore clinical features and prognosis of hepatocellular carcinoma (HCC) in hepatitis B virus surface antigen (HBsAg)-serocleared patients and identify risk factors associated with postoperative recurrence after curative hepatectomy.<h4>Methods</h4>Patients who had undergone initial hepatectomy for HCC from January 2010 through December 2022. Clinicopathological data were compared between HBsAg-seropositive and HBsAg-serocleared patients. Furthermore, risk factors associated with early and late postoperative HCC recurrence (early and late recurrences (ER and LR), respectively) were analyzed for HBsAg-serocleared HCC patients treated by curative hepatectomy.<h4>Results</h4>A total of 2184 consecutive patients undergoing initial hepatectomy for HCC were enrolled, including 33Therapeutic advances in medical oncology17588359241289202https://www.ebi.ac.uk/biostudies/studies/S-EPMC11526261biostudies-literatureHepatocellular carcinoma in HBsAg seroclearance: clinical features, recurrence, and prognosis following curative hepatectomy.PMC11526261Yin XLi BXu WGong HfalseHepatocellular carcinoma in HBsAg seroclearance: clinical features, recurrence, and prognosis following curative hepatectomy.<h4>Aim</h4>To explore clinical features and prognosis of hepatocellular carcinoma (HCC) in hepatitis B virus surface antigen (HBsAg)-serocleared patients and identify risk factors associated with postoperative recurrence after curative hepatectomy.<h4>Methods</h4>Patients who had undergone initial hepatectomy for HCC from January 2010 through December 2022. Clinicopathological data were compared between HBsAg-seropositive and HBsAg-serocleared patients. Furthermore, risk factors associated with early and late postoperative HCC recurrence (early and late recurrences (ER and LR), respectively) were analyzed for HBsAg-serocleared HCC patients treated by curative hepatectomy.<h4>Results</h4>A total of 2184 consecutive patients undergoing initial hepatectomy for HCC were enrolled, including 332024-01-01T00:00:00Z20242025-04-26T17:02:26.719Z2025-04-06T15:21:55.639ZS-EPMC115262613948313810.1177/17588359241289202