{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Oo T"],"funding":["The Research and Academic Services, Khon Kaen University through Research Program Year 2022","The Fundamental Fund of Khon Kaen University"],"pagination":["380"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11526599"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(1)"],"pubmed_abstract":["<h4>Background</h4>Skin commensal bacteria (Staphylococcus epidermidis) can help defend against skin infections, and they are increasingly being recognized for their role in benefiting skin health. This study aims to demonstrate the activities that Myristica fragrans Houtt. seed extracts, crude extract (CE) and essential oil (EO), have in terms of promoting the growth of the skin commensal bacterium S. epidermidis and providing metabolites under culture conditions to disrupt the biofilm formation of the common pathogen Staphylococcus aureus.<h4>Methods</h4>The culture supernatant obtained from a co-culture of S. epidermidis with M. fragrans Houtt. seed extracts in either CE or EO forms were analyzed using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography tandem mass sp"],"journal":["BMC complementary medicine and therapies"],"pubmed_title":["Effectiveness of co-cultured Myristica fragrans Houtt. seed extracts with commensal Staphylococcus epidermidis and its metabolites in antimicrobial activity and biofilm formation of skin pathogenic bacteria."],"pmcid":["PMC11526599"],"funding_grant_id":["PR65-1-Immune-001","PR65-311 1-002"],"pubmed_authors":["Oo T","Saiboonjan B","Mongmonsin U","Lulitanond A","Srijampa S","Tippayawat P","Sutthanut K","Srisrattakarn A","Chanawong A","Tavichakorntrakool R","Roytrakul S"],"additional_accession":[]},"is_claimable":false,"name":"Effectiveness of co-cultured Myristica fragrans Houtt. seed extracts with commensal Staphylococcus epidermidis and its metabolites in antimicrobial activity and biofilm formation of skin pathogenic bacteria.","description":"<h4>Background</h4>Skin commensal bacteria (Staphylococcus epidermidis) can help defend against skin infections, and they are increasingly being recognized for their role in benefiting skin health. This study aims to demonstrate the activities that Myristica fragrans Houtt. seed extracts, crude extract (CE) and essential oil (EO), have in terms of promoting the growth of the skin commensal bacterium S. epidermidis and providing metabolites under culture conditions to disrupt the biofilm formation of the common pathogen Staphylococcus aureus.<h4>Methods</h4>The culture supernatant obtained from a co-culture of S. epidermidis with M. fragrans Houtt. seed extracts in either CE or EO forms were analyzed using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography tandem mass sp","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-05T09:12:14.479Z","creation":"2025-04-05T09:12:14.479Z"},"accession":"S-EPMC11526599","cross_references":{"pubmed":["39482677"],"doi":["10.1186/s12906-024-04675-z"]}}