biostudies-literatureUnknown14(10)Ye L<h4>Introduction</h4>Pain management in patients with cancer is a critical aspect of oncological care, yet remains challenging with current pharmacological therapies. Non-pharmacological interventions, offering potential benefits without the adverse effects of drugs, have gained attention. However, the effectiveness of these diverse non-pharmacological interventions is not well understood, creating a gap in clinical practice. This study aims to conduct a systematic review and network meta-analysis (NMA) to evaluate the efficacy of various non-pharmacological interventions for pain management in patients with cancer, providing evidence-based guidance for clinicians and patients.<h4>Methods and analysis</h4>A systematic review and Bayesian NMA will be performed. To assess the efficacy of intBMJ opene084500https://www.ebi.ac.uk/biostudies/studies/S-EPMC11529465biostudies-literatureEffectiveness of non-pharmacological interventions for pain management in patients with cancer:a protocol for systematic review and network meta-analysis.PMC11529465Ye LHuang YHHuang YXLi DDeng QCPeng YHLi YHfalseEffectiveness of non-pharmacological interventions for pain management in patients with cancer:a protocol for systematic review and network meta-analysis.<h4>Introduction</h4>Pain management in patients with cancer is a critical aspect of oncological care, yet remains challenging with current pharmacological therapies. Non-pharmacological interventions, offering potential benefits without the adverse effects of drugs, have gained attention. However, the effectiveness of these diverse non-pharmacological interventions is not well understood, creating a gap in clinical practice. This study aims to conduct a systematic review and network meta-analysis (NMA) to evaluate the efficacy of various non-pharmacological interventions for pain management in patients with cancer, providing evidence-based guidance for clinicians and patients.<h4>Methods and analysis</h4>A systematic review and Bayesian NMA will be performed. To assess the efficacy of int2024-01-01T00:00:00Z2024 Nov2026-07-16T07:20:47.125Z2025-04-06T15:29:18.755ZS-EPMC115294653948682110.1136/bmjopen-2024-084500