biostudies-literatureUnknown19(8)Lister RC<h4>Background</h4>Extensor pollicis longus (EPL) rupture and tenosynovitis of the third dorsal compartment is often described in association with a history of rheumatoid arthritis or in the setting of a distal radius fracture. However, the literature suggests multiple other potential factors that may lead to a seemingly spontaneous rupture.<h4>Methods</h4>We performed a systematic review following guidelines set forth by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The search consisted of headings and keywords related to tendon injuries, tendinopathy, hand surgery, tendon transfer, and injections, as published in reports and studies. Citations were screened by title and abstract against predetermined inclusion and exclusion criteria by 2 independent reHand (New York, N.Y.)1314-1320https://www.ebi.ac.uk/biostudies/studies/S-EPMC11536720biostudies-literatureSpontaneous Rupture of the Extensor Pollicis Longus Tendon: A Systematic Review.PMC11536720Carr CWBradford HCDelancy ALister RCNaram AShufflebarger JVJoo ARothkopf DMfalseSpontaneous Rupture of the Extensor Pollicis Longus Tendon: A Systematic Review.<h4>Background</h4>Extensor pollicis longus (EPL) rupture and tenosynovitis of the third dorsal compartment is often described in association with a history of rheumatoid arthritis or in the setting of a distal radius fracture. However, the literature suggests multiple other potential factors that may lead to a seemingly spontaneous rupture.<h4>Methods</h4>We performed a systematic review following guidelines set forth by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The search consisted of headings and keywords related to tendon injuries, tendinopathy, hand surgery, tendon transfer, and injections, as published in reports and studies. Citations were screened by title and abstract against predetermined inclusion and exclusion criteria by 2 independent re2024-01-01T00:00:00Z2024 Nov2026-06-05T07:40:43.88Z2026-05-14T03:12:47.111ZS-EPMC115367203726912410.1177/15589447231175513