<HashMap><database>biostudies-literature</database><scores/><additional><omics_type>Unknown</omics_type><volume>20(33)</volume><submitter>Ramalingam SS</submitter><funding>Pfizer</funding><pubmed_abstract>Drs. Ramalingam and Carlisle discuss the incidence and pathophysiology of BRAF V600E-mutant metastatic non-small cell lung cancer and current treatment options. The podcast provides an overview of the data from the recent Pfizer-sponsored phase 2 PHAROS (NCT03915951) study, which were the basis for the recent US Food and Drug Administration approval of encorafenib plus binimetinib for BRAF V600E-mutant metastatic non-small cell lung cancer.</pubmed_abstract><journal>Future oncology (London, England)</journal><pagination>2503-2508</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC11537293</full_dataset_link><repository>biostudies-literature</repository><pubmed_title>Encorafenib plus binimetinib for BRAF V600E-mutant metastatic NSCLC: clinical implications of the phase 2 PHAROS study.</pubmed_title><pmcid>PMC11537293</pmcid><pubmed_authors>Carlisle JW</pubmed_authors><pubmed_authors>Ramalingam SS</pubmed_authors></additional><is_claimable>false</is_claimable><name>Encorafenib plus binimetinib for BRAF V600E-mutant metastatic NSCLC: clinical implications of the phase 2 PHAROS study.</name><description>Drs. Ramalingam and Carlisle discuss the incidence and pathophysiology of BRAF V600E-mutant metastatic non-small cell lung cancer and current treatment options. The podcast provides an overview of the data from the recent Pfizer-sponsored phase 2 PHAROS (NCT03915951) study, which were the basis for the recent US Food and Drug Administration approval of encorafenib plus binimetinib for BRAF V600E-mutant metastatic non-small cell lung cancer.</description><dates><release>2024-01-01T00:00:00Z</release><publication>2024</publication><modification>2025-04-04T18:53:54.856Z</modification><creation>2025-04-04T18:53:54.856Z</creation></dates><accession>S-EPMC11537293</accession><cross_references><pubmed>39225598</pubmed><doi>10.1080/14796694.2024.2391270</doi></cross_references></HashMap>