{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang JG"],"funding":["Self-Funded Scientific Research Project of Guangxi Zhuang Autonomous Region Health Commission"],"pagination":["e40245"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11537629"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["103(44)"],"pubmed_abstract":["<h4>Background</h4>To explore the relationship between vitamin D levels and risk of SARS-CoV-2 infection and its severity in children and adolescents, and provide a theoretical basis for clinical practice.<h4>Methods</h4>The PubMed, Web of Science, Embase, MEDLINE, and Cochrane Library databases were searched for comprehensive cohort and case-control studies on the association between childhood vitamin D deficiency and the risk and prognosis of coronavirus disease-2019 (COVID-19). The search period was set from December 1, 2019, to December 31, 2023.<h4>Results</h4>The vitamin D insufficiency rate in children with COVID-19 was 80.78% (95% CI, 62.6% to 93.89%), with a deficiency rate of 32% (95% CI: 19.01% to 46.61%). Vitamin D insufficiency was more common in children with COVID-19 than in"],"journal":["Medicine"],"pubmed_title":["Vitamin D levels in children and adolescents are associated with coronavirus disease-2019 outcomes: A systematic review and meta-analysis."],"pmcid":["PMC11537629"],"funding_grant_id":["Z20210123"],"pubmed_authors":["Liang QY","Wang JG","Dou HH"],"additional_accession":[]},"is_claimable":false,"name":"Vitamin D levels in children and adolescents are associated with coronavirus disease-2019 outcomes: A systematic review and meta-analysis.","description":"<h4>Background</h4>To explore the relationship between vitamin D levels and risk of SARS-CoV-2 infection and its severity in children and adolescents, and provide a theoretical basis for clinical practice.<h4>Methods</h4>The PubMed, Web of Science, Embase, MEDLINE, and Cochrane Library databases were searched for comprehensive cohort and case-control studies on the association between childhood vitamin D deficiency and the risk and prognosis of coronavirus disease-2019 (COVID-19). The search period was set from December 1, 2019, to December 31, 2023.<h4>Results</h4>The vitamin D insufficiency rate in children with COVID-19 was 80.78% (95% CI, 62.6% to 93.89%), with a deficiency rate of 32% (95% CI: 19.01% to 46.61%). Vitamin D insufficiency was more common in children with COVID-19 than in","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2025-04-04T03:06:08.781Z","creation":"2025-04-04T03:06:08.781Z"},"accession":"S-EPMC11537629","cross_references":{"pubmed":["39495975"],"doi":["10.1097/MD.0000000000040245"]}}