biostudies-literatureUnknown66(1)Myrenas M<h4>Background</h4>Bovine respiratory disease (BRD) is common in intensively raised cattle and is often treated with antibiotics. For practitioners, knowledge of the bacteria involved in an outbreak and their antibiotic susceptibility is warranted. To this end, samples from the upper or lower respiratory tract of calves can be submitted for bacteriological culture and susceptibility testing of relevant isolates. However, it is debated whether isolates from the upper respiratory tract are representative of bacteria causing infections in the lower respiratory tract. In this study, we used MALDI-TOF MS, multilocus sequence typing (MLST) and core-genome multilocus sequence typing (cgMLST) to compare culture results of 219 paired samples (sample pairs) of deep nasal swabs (DNS) and tracheobroncActa veterinaria Scandinavica58https://www.ebi.ac.uk/biostudies/studies/S-EPMC11539715biostudies-literaturePasteurella multocida from deep nasal swabs and tracheobronchial lavage in bovine calves from Sweden.PMC11539715Bengtsson BMyrenas MHarbom BPringle MfalsePasteurella multocida from deep nasal swabs and tracheobronchial lavage in bovine calves from Sweden.<h4>Background</h4>Bovine respiratory disease (BRD) is common in intensively raised cattle and is often treated with antibiotics. For practitioners, knowledge of the bacteria involved in an outbreak and their antibiotic susceptibility is warranted. To this end, samples from the upper or lower respiratory tract of calves can be submitted for bacteriological culture and susceptibility testing of relevant isolates. However, it is debated whether isolates from the upper respiratory tract are representative of bacteria causing infections in the lower respiratory tract. In this study, we used MALDI-TOF MS, multilocus sequence typing (MLST) and core-genome multilocus sequence typing (cgMLST) to compare culture results of 219 paired samples (sample pairs) of deep nasal swabs (DNS) and tracheobronc2024-01-01T00:00:00Z2024 Nov2026-07-01T03:18:03.736Z2025-04-04T01:17:50.941ZS-EPMC115397153950128210.1186/s13028-024-00781-7