{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wu J"],"funding":["Fundamental Research Funds for the Central Universities","Natural Science Foundation of Chongqing","National Center of Technology Innovation for Pigs"],"pagination":["3103"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11544765"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(21)"],"pubmed_abstract":["In 2022, a significant PRV outbreak in a southwestern China pig farm led to a high incidence of sow abortion. A serological analysis using <i>gE</i> antigen-based ELISA revealed a high prevalence (69.30%) of PRV <i>gE</i> antibodies among the affected pigs, with a significant variation across different pig populations (1.11-76.12%). We collected additional 5552 pig serum samples and 580 pig cerebrospinal fluid (CSF) samples from various pig farms in Southwest China between 2022 and 2024. The seropositive rates for PRV <i>gE</i> antibodies ranged from 2.36% and 8.65% in the serum samples, while the positive detection rates for the PRV <i>gE</i> gene in the cerebrospinal fluid samples, as determined by PCR, were between 1.06% and 2.36%. The PCR analysis and sequencing of the PRV <i>gB</i>, <"],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Prevalence and Genetic Variation Investigation of the Pseudorabies Virus in Southwest China."],"pmcid":["PMC11544765"],"funding_grant_id":["SWU-KR22036","CSTB2024NSCQ-MSX0467","NCTIP-XD/C09"],"pubmed_authors":["Wu J","Zhu J","Zhang J","Yan N","Luo Y","Yang R","Fu L","Wang X","Zhang L","Jia M","Wang Y","Zhou J"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and Genetic Variation Investigation of the Pseudorabies Virus in Southwest China.","description":"In 2022, a significant PRV outbreak in a southwestern China pig farm led to a high incidence of sow abortion. A serological analysis using <i>gE</i> antigen-based ELISA revealed a high prevalence (69.30%) of PRV <i>gE</i> antibodies among the affected pigs, with a significant variation across different pig populations (1.11-76.12%). We collected additional 5552 pig serum samples and 580 pig cerebrospinal fluid (CSF) samples from various pig farms in Southwest China between 2022 and 2024. The seropositive rates for PRV <i>gE</i> antibodies ranged from 2.36% and 8.65% in the serum samples, while the positive detection rates for the PRV <i>gE</i> gene in the cerebrospinal fluid samples, as determined by PCR, were between 1.06% and 2.36%. The PCR analysis and sequencing of the PRV <i>gB</i>, <","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-05-26T20:04:18.491Z","creation":"2025-04-04T23:32:30.637Z"},"accession":"S-EPMC11544765","cross_references":{"pubmed":["39518826"],"doi":["10.3390/ani14213103"]}}