biostudies-literatureCorrea ANRConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)National Council for Scientific and Technological Development3403https://www.ebi.ac.uk/biostudies/studies/S-EPMC11544775biostudies-literatureUnknown13(21)This study investigates the antifungal potential of encapsulated essential oil (EO) from <i>Baccharis dracunculifolia</i> and nerolidol (NE) within Pluronic^® F-127 nanoparticles (NPs). The EO, containing nerolidol, β-caryophyllene, and α-pinene as major bioactive compounds, exhibited superior antifungal activity compared to NE. The NP-EO formulations demonstrated high efficacy against <i>Botrytis cinerea</i>, with inhibition rates ranging from 29.73% to 87.60% and moderate efficacy against <i>Rhizopus</i> sp., with inhibition rates from 11.81% to 32.73%. In comparison, NP-NE showed lower antifungal activity. Both formulations effectively inhibited spore germination, with NP-EO showing greater inhibition compared to NP-NE. The encapsulation efficiency was significantly higher forFoods (Basel, Switzerland)Inhibition of Food Spoilage Fungi, <i>Botrytis cinerea</i> and <i>Rhizopus</i> sp., by Nanoparticles Loaded with <i>Baccharis dracunculifolia</i> Essential Oil and Nerolidol.PMC11544775308880/2021-8405165/2023-4Clerici NJde Paula NOBrandelli ACorrea ANRfalseInhibition of Food Spoilage Fungi, <i>Botrytis cinerea</i> and <i>Rhizopus</i> sp., by Nanoparticles Loaded with <i>Baccharis dracunculifolia</i> Essential Oil and Nerolidol.This study investigates the antifungal potential of encapsulated essential oil (EO) from <i>Baccharis dracunculifolia</i> and nerolidol (NE) within Pluronic^® F-127 nanoparticles (NPs). The EO, containing nerolidol, β-caryophyllene, and α-pinene as major bioactive compounds, exhibited superior antifungal activity compared to NE. The NP-EO formulations demonstrated high efficacy against <i>Botrytis cinerea</i>, with inhibition rates ranging from 29.73% to 87.60% and moderate efficacy against <i>Rhizopus</i> sp., with inhibition rates from 11.81% to 32.73%. In comparison, NP-NE showed lower antifungal activity. Both formulations effectively inhibited spore germination, with NP-EO showing greater inhibition compared to NP-NE. The encapsulation efficiency was significantly higher for2024-01-01T00:00:00Z2024 Oct2026-07-12T03:21:38.476Z2025-04-04T18:56:19.096ZS-EPMC115447753951718710.3390/foods13213403