{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lv X"],"funding":["This study was funded by the National Natural Science Foundation of China (32302693), the Natural Science Foundation of Jiangsu Province (BK20230584), National Natural Science Founda-tion of China-CGIAR (32061143036), Jiangsu 333 Distinguished Talents Pro"],"pagination":["11547"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11546337"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(21)"],"pubmed_abstract":["A series of differentially expressed circular RNAs (circRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) were identified through sequencing in the hair follicle tissues of Hu sheep with small-waved and straight wool patterns. Based on these findings, the circCSPP1-miR-10a-<i>BMP7</i> (Bone Morphogenetic Protein 7) regulatory network was constructed. The preliminary study highlighted that miR-10a and the BMP7 gene exhibited not only significant differential expression across hair follicle tissues with different patterns in Hu sheep but also had an impact on the proliferation of hair papilla cells. The proliferation of hair papilla cells is intricately linked to hair follicle development and growth. Consequently, we selected the circCSPP1-miR-10a-<i>BMP7</i> regulatory network to valida"],"journal":["International journal of molecular sciences"],"pubmed_title":["CircCSPP1 Competitively Binds miR-10a to Regulate BMP7 Expression and Affects the Proliferation of Dermal Papilla Cells."],"pmcid":["PMC11546337"],"funding_grant_id":["32302693, BK20230584, 32061143036, (2022) 2-323, 22KJD230003, 22KJA230001, YZ2023070"],"pubmed_authors":["Li Y","Lv X","Sun W","Wang J","Zhou H","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"CircCSPP1 Competitively Binds miR-10a to Regulate BMP7 Expression and Affects the Proliferation of Dermal Papilla Cells.","description":"A series of differentially expressed circular RNAs (circRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) were identified through sequencing in the hair follicle tissues of Hu sheep with small-waved and straight wool patterns. Based on these findings, the circCSPP1-miR-10a-<i>BMP7</i> (Bone Morphogenetic Protein 7) regulatory network was constructed. The preliminary study highlighted that miR-10a and the BMP7 gene exhibited not only significant differential expression across hair follicle tissues with different patterns in Hu sheep but also had an impact on the proliferation of hair papilla cells. The proliferation of hair papilla cells is intricately linked to hair follicle development and growth. Consequently, we selected the circCSPP1-miR-10a-<i>BMP7</i> regulatory network to valida","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-22T16:27:52.151Z","creation":"2025-04-06T01:46:09.699Z"},"accession":"S-EPMC11546337","cross_references":{"pubmed":["39519100"],"doi":["10.3390/ijms252111547"]}}