{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sultana S"],"funding":["University of Western Australia"],"pagination":["5161"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11547264"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(21)"],"pubmed_abstract":["This is the first study to report on high performance thin layer chromatography (HPTLC) generated spectrophotometric data to systematically capture flavonoid compounds using optimized derivatization with either AlCl<sub>3</sub> or NaNO<sub>2</sub>-AlCl<sub>3</sub>-NaOH as visualisation reagents. While the traditional AlCl<sub>3</sub> colorimetric method using UV-Vis analysis provides valuable insights into the presence of flavonoids and allows derivation of the total flavonoid content (TFC) of a sample, HPTLC fingerprints obtained after spraying with AlCl<sub>3</sub> or NaNO<sub>2</sub>-AlCl<sub>3</sub>-NaOH enable the visualization of the various flavonoids present in a sample based on their respective absorption shifts, thus complementing the traditional TFC assay. In this study, 40 diff"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Investigating Flavonoids by HPTLC Analysis Using Aluminium Chloride as Derivatization Reagent."],"pmcid":["PMC11547264"],"funding_grant_id":["N/A"],"pubmed_authors":["Foster KJ","Hossain ML","Lim LY","Sultana S","Locher C","Sostaric T"],"additional_accession":[]},"is_claimable":false,"name":"Investigating Flavonoids by HPTLC Analysis Using Aluminium Chloride as Derivatization Reagent.","description":"This is the first study to report on high performance thin layer chromatography (HPTLC) generated spectrophotometric data to systematically capture flavonoid compounds using optimized derivatization with either AlCl<sub>3</sub> or NaNO<sub>2</sub>-AlCl<sub>3</sub>-NaOH as visualisation reagents. While the traditional AlCl<sub>3</sub> colorimetric method using UV-Vis analysis provides valuable insights into the presence of flavonoids and allows derivation of the total flavonoid content (TFC) of a sample, HPTLC fingerprints obtained after spraying with AlCl<sub>3</sub> or NaNO<sub>2</sub>-AlCl<sub>3</sub>-NaOH enable the visualization of the various flavonoids present in a sample based on their respective absorption shifts, thus complementing the traditional TFC assay. In this study, 40 diff","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2025-04-04T00:38:50.817Z","creation":"2025-04-04T00:38:50.817Z"},"accession":"S-EPMC11547264","cross_references":{"pubmed":["39519802"],"doi":["10.3390/molecules29215161"]}}