{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Arafa WAA"],"funding":["Al Jouf University"],"pagination":["5114"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11547704"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(21)"],"pubmed_abstract":["Our novel binuclear complex-anchored Ru(III) catalyst, designed and assembled by sonicating 2,2'-(4,6-dihydroxy-1,3-phenylene)bis(1<i>H</i>-benzo[<i>d</i>]imidazole-4-carboxylic acid), Ru(DMSO)<sub>4</sub>Cl<sub>2</sub> and 4-methylpyridine, demonstrates remarkable efficiency and selectivity. It promotes one-pot reactions, including active methylenes and benzyl alcohols in water, via a tandem aerobic oxidation/Knoevenagel condensation process, yielding benzylidene malononitrile in excellent yields. The catalyst's ability to oxidize benzyl alcohols to aldehydes, which then undergo Knoevenagel condensation with active methylenes, makes it a multifunctional catalyst. Notably, the catalyst can be successfully retrieved and recycled for five successive rounds with no significant decrease in cat"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["A Ru-Based Complex for Sustainable One-Pot Tandem Aerobic Oxidation-Knoevenagel Condensation Reactions."],"pmcid":["PMC11547704"],"funding_grant_id":["DGSSR-2023-02-02344"],"pubmed_authors":["Arafa WAA","Mourad AK","Brase S","Nayl AA","Youssef AMS","Ahmed IM"],"additional_accession":[]},"is_claimable":false,"name":"A Ru-Based Complex for Sustainable One-Pot Tandem Aerobic Oxidation-Knoevenagel Condensation Reactions.","description":"Our novel binuclear complex-anchored Ru(III) catalyst, designed and assembled by sonicating 2,2'-(4,6-dihydroxy-1,3-phenylene)bis(1<i>H</i>-benzo[<i>d</i>]imidazole-4-carboxylic acid), Ru(DMSO)<sub>4</sub>Cl<sub>2</sub> and 4-methylpyridine, demonstrates remarkable efficiency and selectivity. It promotes one-pot reactions, including active methylenes and benzyl alcohols in water, via a tandem aerobic oxidation/Knoevenagel condensation process, yielding benzylidene malononitrile in excellent yields. The catalyst's ability to oxidize benzyl alcohols to aldehydes, which then undergo Knoevenagel condensation with active methylenes, makes it a multifunctional catalyst. Notably, the catalyst can be successfully retrieved and recycled for five successive rounds with no significant decrease in cat","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-07-09T13:25:13.835Z","creation":"2025-04-04T00:38:37.664Z"},"accession":"S-EPMC11547704","cross_references":{"pubmed":["39519755"],"doi":["10.3390/molecules29215114"]}}