{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2(3)"],"submitter":["Guo W"],"pubmed_abstract":["<h4>Aims</h4>A new model of computational fluid dynamics (CFD)-based algorithm for coronary CT angiography (CCTA)-derived fractional flow reserve (FFR) (CT-FFR) analysis by expanding the coronary tree to smaller-diameter lumen (0.8 mm) using Newton-Krylov-Schwarz (NKS) method to solve the three-dimensional time-dependent incompressible Navier-Stokes equations has been developed; however, the diagnostic performance of this new method has not been sufficiently investigated. The aim of this study was to determine the diagnostic performance of a novel CT-FFR technique by expanding the coronary tree in the CFD domain.<h4>Methods and results</h4>Six centres enrolled 338 symptomatic patients with suspected or known coronary artery disease (CAD) who prospectively underwent CCTA and FFR. Stenosis a"],"journal":["European heart journal. Imaging methods and practice"],"pagination":["qyae106"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11547952"],"repository":["biostudies-literature"],"pubmed_title":["CT-FFR by expanding coronary tree with Newton-Krylov-Schwarz method to solve the governing equations of CFD."],"pmcid":["PMC11547952"],"pubmed_authors":["Shen L","Wu J","Gao B","Liu J","Jun J","Huang J","Lu Y","Guo W","Hu X","Zhang H","Ge J","Wei W","Wang J","Cheng Z","Yao Z","Jin H","Yan Z","Liang J","Wang X","Zhou H","Tong G","Chen R","Wu Y","Li C","Zeng M","He W","Yang R","Yang S","Yin J"],"additional_accession":[]},"is_claimable":false,"name":"CT-FFR by expanding coronary tree with Newton-Krylov-Schwarz method to solve the governing equations of CFD.","description":"<h4>Aims</h4>A new model of computational fluid dynamics (CFD)-based algorithm for coronary CT angiography (CCTA)-derived fractional flow reserve (FFR) (CT-FFR) analysis by expanding the coronary tree to smaller-diameter lumen (0.8 mm) using Newton-Krylov-Schwarz (NKS) method to solve the three-dimensional time-dependent incompressible Navier-Stokes equations has been developed; however, the diagnostic performance of this new method has not been sufficiently investigated. The aim of this study was to determine the diagnostic performance of a novel CT-FFR technique by expanding the coronary tree in the CFD domain.<h4>Methods and results</h4>Six centres enrolled 338 symptomatic patients with suspected or known coronary artery disease (CAD) who prospectively underwent CCTA and FFR. Stenosis a","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2025-04-04T13:41:44.848Z","creation":"2025-04-04T13:41:44.848Z"},"accession":"S-EPMC11547952","cross_references":{"pubmed":["39525515"],"doi":["10.1093/ehjimp/qyae106"]}}