{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(21)"],"submitter":["Yang S"],"pubmed_abstract":["<h4>Background</h4>Many clinical practice guidelines recommend dietary pulses for the prevention and management of cardiovascular disease and diabetes. The impact of extracted pulse proteins remains unclear. We therefore conducted a systematic review and meta-analysis of randomized controlled trials of the effect of extracted pulse proteins on therapeutic lipid targets.<h4>Methods and findings</h4>MEDLINE, Embase, and the Cochrane Library were searched through April 2024 for trials of ≥3-weeks. The primary outcome was low-density lipoprotein-cholesterol (LDL-C). The secondary outcomes were other lipid targets. Independent reviewers extracted data and assessed the risk of bias. Subgroup analyses included by pulse type and the certainty of evidence was assessed using GRADE.<h4>Results</h4>Se"],"journal":["Nutrients"],"pagination":["3765"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11548137"],"repository":["biostudies-literature"],"pubmed_title":["Effects of Extracted Pulse Proteins on Lipid Targets for Cardiovascular Risk Reduction: Systematic Review and Meta-Analysis of Randomized Controlled Trials."],"pmcid":["PMC11548137"],"pubmed_authors":["Mejia SB","Kendall CWC","Ayoub-Charette S","de Souza RJ","Marinangeli CPF","Leiter LA","Jenkins DJA","Ahmad E","Khan TA","Chen V","Vuksan V","Lin EJ","Zurbau A","Back S","Gahagan J","Ha V","English MM","Beyene J","Haintz L","Sievenpiper JL","Chen YT","Chiavaroli L","Yang S","Grant SM","Josse RG"],"additional_accession":[]},"is_claimable":false,"name":"Effects of Extracted Pulse Proteins on Lipid Targets for Cardiovascular Risk Reduction: Systematic Review and Meta-Analysis of Randomized Controlled Trials.","description":"<h4>Background</h4>Many clinical practice guidelines recommend dietary pulses for the prevention and management of cardiovascular disease and diabetes. The impact of extracted pulse proteins remains unclear. We therefore conducted a systematic review and meta-analysis of randomized controlled trials of the effect of extracted pulse proteins on therapeutic lipid targets.<h4>Methods and findings</h4>MEDLINE, Embase, and the Cochrane Library were searched through April 2024 for trials of ≥3-weeks. The primary outcome was low-density lipoprotein-cholesterol (LDL-C). The secondary outcomes were other lipid targets. Independent reviewers extracted data and assessed the risk of bias. Subgroup analyses included by pulse type and the certainty of evidence was assessed using GRADE.<h4>Results</h4>Se","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-07-09T13:26:10.393Z","creation":"2025-04-06T02:54:11.817Z"},"accession":"S-EPMC11548137","cross_references":{"pubmed":["39519598"],"doi":["10.3390/nu16213765"]}}