biostudies-literatureUnknown19(11)Hu X<h4>Background</h4>While the pericapsular nerve group (PENG) block has become increasingly popular for managing pain after hip surgery, its efficacy remains controversial.<h4>Methods</h4>We systematically searched Pubmed, Web of Science, Embase, and the Cochrane Library for randomized controlled trials to assess current evidence about the efficacy of the PENG block. Patients who received PENG block were compared to those who received sham/no block in terms of opioid consumption and pain within 24h after surgery, time to first opioid requirement, functional recovery, risk of nausea and vomiting, and patient dissatisfaction. The quality of evidence was assessed using the "Grading of Recommendations Assessment, Development and Evaluation" (GRADE) system.<h4>Results</h4>We meta-analyzed six trPloS onee0310008https://www.ebi.ac.uk/biostudies/studies/S-EPMC11548832biostudies-literaturePericapsular nerve group block reduces opioid use and pain after hip surgery: A systematic review and meta-analysis of randomized controlled trials.PMC11548832Sheng HHuang YXu BHu XZhang SChenyang DLao YfalsePericapsular nerve group block reduces opioid use and pain after hip surgery: A systematic review and meta-analysis of randomized controlled trials.<h4>Background</h4>While the pericapsular nerve group (PENG) block has become increasingly popular for managing pain after hip surgery, its efficacy remains controversial.<h4>Methods</h4>We systematically searched Pubmed, Web of Science, Embase, and the Cochrane Library for randomized controlled trials to assess current evidence about the efficacy of the PENG block. Patients who received PENG block were compared to those who received sham/no block in terms of opioid consumption and pain within 24h after surgery, time to first opioid requirement, functional recovery, risk of nausea and vomiting, and patient dissatisfaction. The quality of evidence was assessed using the "Grading of Recommendations Assessment, Development and Evaluation" (GRADE) system.<h4>Results</h4>We meta-analyzed six tr2024-01-01T00:00:00Z20242025-04-04T00:38:46.679Z2025-04-04T00:38:46.679ZS-EPMC115488323951454010.1371/journal.pone.0310008